Calcitriol
From Wikipedia, the free encyclopedia
Calcitriol is a form of Vitamin D3 with three alcohol groups. It increases gastrointestinal calcium absorption, stimulates osteoclastic calcium resorption from bone, facilitates the effect parathyroid hormone (PTH) has on bone resorption, and increases renal tubular absorption of calcium. Production of calcitriol by the cells of the Proximal Tubule of the nephron in the kidney is stimulated by hypocalcemia and hypophosphatemia as well as parathyroid hormone.
Types include:
- 1,25-dihydroxycholecalciferol (when not further specified, this is usually what is meant by "calcitriol")
- 24,25-dihydroxycholecalciferol
Because cholecalciferol already has one alcohol group, only two are further specified in the nomenclature.
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