File:Components-of-the-tumor-microenvironment.png
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Summary
| Description |
English: Component of the tumor microenvironment (TME). The tumor microenvironment is a complex system of various tumor cells, stromal cells, and immune cells. It is characterized by dysregulated vasculature and collagen, which results in poor perfusion and densely-packed glycolytic tumor cells. This creates pockets of low oxygen levels, acidic pH, poor nutrient loads, anti-inflammatory cytokines, chemokines, and metabolic by-products, such as lactate. Both myeloid and lymphoid immune cells infiltrate the tumor microenvironment (TME).
Figure created using BioRender.com. |
| Date | |
| Source | Hepatic tumor microenvironments and effects on NK cell phenotype and function. 2019. International journal of molecular sciences, 20(17), 4131. [1]https://doi.org/10.3390/ijms20174131 |
| Author | Piñeiro Fernández, J., Luddy, K. A., Harmon, C., & O’Farrelly, C. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 15:30, 28 March 2024 | | 850 × 680 (155 KB) | Fabi Fuu 76 | Uploaded a work by Piñeiro Fernández, J., Luddy, K. A., Harmon, C., & O’Farrelly, C. from Piñeiro Fernández, J., Luddy, K. A., Harmon, C., & O’Farrelly, C. (2019). Hepatic tumor microenvironments and effects on NK cell phenotype and function. International journal of molecular sciences, 20(17), 4131. with UploadWizard |
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