File:DNA DSB TOP2B PARP-1 complex with NHEJ enzymes.jpg

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Summary

Description
English: Paused RNA polymerase and limited short-term TOP2B-induced DNA double-strand break. The 5' ends of DNA are covalently joined to tyrosine within the TOP2B dimer complexed with PARP-1. The NHEJ repair pathway components DNA-PKcs, KU70/KU80 and DNA LIGASE IV are also associated with the TOP2B dimer-PARP-1 complex.
Date
Source Own work
Author MethylC5

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Captions

Paused RNA polymerase and limited, short-term TOP2B-induced DNA double-strand break with associated PARP-1 and NHEJ complex enzymes

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28 May 2022

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Date/TimeThumbnailDimensionsUserComment
current20:18, 28 May 2022Thumbnail for version as of 20:18, 28 May 20222,132 × 990 (368 KB)MethylC5Uploaded own work with UploadWizard
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