File:Genome of enteroviruses and aphthoviruses.png
Size of this preview: 796 × 599 pixels. Other resolutions: 319 × 240 pixels | 638 × 480 pixels | 1,020 × 768 pixels | 1,280 × 964 pixels | 2,560 × 1,928 pixels | 3,354 × 2,526 pixels.
Original file (3,354 × 2,526 pixels, file size: 443 KB, MIME type: image/png)
 | This is a file from the Wikimedia Commons. Information from its description page there is shown below. Commons is a freely licensed media file repository. You can help. |
Summary
| Description |
English: Genome organization and expression of enteroviruses and aphthoviruses. Viral RNA (vRNA) is polyadenylated and covalently linked to a virus-encoded protein (3B) at its 5′ end. Cleavages facilitated by 2Apro of the enteroviruses (black arrow) or by an NPG↓P motif at the C-terminus of 2A of foot-and-mouth disease virus (white arrow) release the P1 and P1-2A proteins, respectively. The leader proteinase Lpro releases itself from the polyprotein by cleavage at its own C-terminus. P2 and P3 polypeptides are precursors of the nonstructural proteins necessary for genome replication. Further polyprotein processing is mediated by 3Cpro (cleavage sites indicated by arrow heads). Processing of 1AB, the precursor of 1A and 1B, is thought to be autocatalytic and occurs in empty capsids or at virion maturation (white diamond). |
| Date | |
| Source | https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000911 |
| Author | R. Zell, E. Delwart, A. E. Gorbalenya, T. Hovi, A. M. Q. King, N. J. Knowles, A. M. Lindberg, M. A. Pallansch, A. C. Palmenberg, G. Reuter, P. Simmonds, T. Skern, G. Stanway, T. Yamashita, and ICTV Report Consortium |
Licensing
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 09:38, 7 June 2020 | | 3,354 × 2,526 (443 KB) | Guest2625 | Uploaded a work by R. Zell, E. Delwart, A. E. Gorbalenya, T. Hovi, A. M. Q. King, N. J. Knowles, A. M. Lindberg, M. A. Pallansch, A. C. Palmenberg, G. Reuter, P. Simmonds, T. Skern, G. Stanway, T. Yamashita, and ICTV Report Consortium from https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000911 with UploadWizard |
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):
