File:PARP1 binding olaparib 5DS3.png

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Summary

Description Mixed surface–ribbon representation of the catalytic domain of human poly (ADP-ribose) polymerase 1 (PARP1) binding the small-molecule inhibitor olaparib (shown as a space-filling model). Representation-independent color control was used to color the surface and ribbon diagrams differentially in the interest of clarity.
 
This structure was created with PyMOL.
Date
Source

From PDB entry 5DS3. More information:

  • Dawicki-McKenna JM, Langelier MF, Denizio JE, et al. PARP-1 activation requires local unfolding of an autoinhibitory domain. Mol Cell. 2015;60(5):755-68. doi:10.1016/j.molcel.2015.10.013
Author Fvasconcellos (talk · contribs)
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11 August 2017

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Date/TimeThumbnailDimensionsUserComment
current04:54, 11 August 2017Thumbnail for version as of 04:54, 11 August 20171,440 × 1,207 (1.12 MB)Fvasconcellos=={{int:filedesc}}== {{Information |Description=Mixed surface–ribbon representation of the {{w|catalytic domain}} of human {{w|poly (ADP-ribose) polymerase}} 1 ({{w|PARP1}}) binding the small-molecule inhibitor {{w|olaparib}} (shown as a {{w|space-fi...
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