File:Trifluoroisopropanolamine SEGRA.svg

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Summary

DescriptionTrifluoroisopropanolamine SEGRA.svg	English: Basic structure of selective glucocorticoid receptor agonists of the trifluoropropanolamine/-amide type, with some examples.
Date	20 March 2010
Source	Own work, structures from: Schäcke, H; Schottelius, A; Döcke, Wd; Strehlke, P; Jaroch, S; Schmees, N; Rehwinkel, H; Hennekes, H; Asadullah, K (Jan 2004). "Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects." (Free full text). Proceedings of the National Academy of Sciences of the United States of America 101 (1): 227–32. DOI:10.1073/pnas.0300372101. PMID 14694204. PMC: 314167. Mealy, N; Dulsat, C (2009). "36th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF)". Drugs Fut 34 (4): 341. Biggadike, Keith; Boudjelal, Mohamed; Clackers, Margaret; Coe, Diane M.; Demaine, Derek A.; Hardy, George W.; Humphreys, Davina; Inglis, Graham G. A.; Johnston, Michael J. (2007). "Nonsteroidal Glucocorticoid Agonists: Tetrahydronaphthalenes with Alternative Steroidal A-Ring Mimetics Possessing Dissociated (Transrepression/Transactivation) Efficacy Selectivity". Journal of Medicinal Chemistry 50 (26): 6519. DOI:10.1021/jm070778w. PMID 18038970.
Author	Anypodetos
SVG development InfoField	The source code of this SVG is invalid due to an error. This W3C-invalid structural formula was created with BKchem-Inkscape. The chemistry symbols of this structural formula are drawn using the path text method.

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File history

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	Date/Time	Dimensions	User	Comment
current	20:26, 13 September 2010	550 × 601 (152 KB)	Anypodetos	BOL-303242-X = mapracorat
	20:06, 1 April 2010	550 × 601 (155 KB)	Anypodetos	Clarified stereochemistry
	12:53, 21 March 2010	550 × 601 (154 KB)	Anypodetos	Superscript numbering for R's
	13:27, 20 March 2010	550 × 601 (155 KB)	Anypodetos	Show R configuration of asymmetric carbon
	12:39, 20 March 2010	550 × 601 (152 KB)	Anypodetos	{{Information \|Description={{en\|1=Basic structure of w:selective glucocorticoid receptor agonists of the trifluoroisopropanolamine type, with some examples.}} \|Source={{own}} \|Author=Anypodetos \|Date=2010-03-20 \|Permission= \|other