File:VarianceAccountedFor YongRabenLelloHsu.png
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Summary
| Description |
English: Polygenic risk predictors predicts disease risk by selecting a subset of Single Nucleotide Polymorphisms (SNPs) – genetic variations at a single base pair in the DNA – and calculating a risk score as a function of these selected SNPs. The graph illustrates how many of these SNPs are located within, or close to, regions in the DNA that code for proteins. The horizontal axis describes the window sizes of the inclusions. At 0, only SNPs that are within coding regions are included whereas all SNPs within 30,000 base pairs from a coding region are included at the very right of the graph. The particular predictors in the graph were trained using the LASSO-algorithm. |
| Date | |
| Source | https://www.nature.com/articles/s41598-020-68881-8 |
| Author | Yong SY, Raben TG, Lello L, Hsu SD |
| Permission (Reusing this file) |
CC BY 4.0 |
Licensing
This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 14:09, 3 May 2021 | | 2,644 × 1,506 (915 KB) | Stal potaten | Uploaded a work by Yong SY, Raben TG, Lello L, Hsu SD from https://www.biorxiv.org/content/10.1101/2020.02.12.946608v1.full with UploadWizard |
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