2-C-Methylerythritol 4-phosphate
Appearance
(Redirected from 2-C-methyl-D-erythritol 4-phosphate)
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Names | |
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IUPAC name
2-C-Methyl-D-erythritol 4-(dihydrogen phosphate)
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Systematic IUPAC name
(2R,3S)-2,3,4-Trihydroxy-3-methylbutyl dihydrogen phosphate | |
Other names
2-C-Methylerythritol 4-phosphate
Methyl-D-erythritol phosphate | |
Identifiers | |
3D model (JSmol)
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Abbreviations | MEP |
ChEBI | |
ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C5H13O7P | |
Molar mass | 216.126 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2-C-Methyl-D-erythritol 4-phosphate (MEP) is an intermediate on the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis.[1] It is the first committed metabolite on that pathway on the route to IPP and DMAPP.
See also
[edit]- DXP reductoisomerase
- MEP pathway (formerly known as the non-mevalonate pathway)
- Fosmidomycin
References
[edit]- ^ Takahashi S, Kuzuyama T, Watanabe H, Seto H (1998). "A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 9879–84. Bibcode:1998PNAS...95.9879T. doi:10.1073/pnas.95.17.9879. PMC 21430. PMID 9707569.
External links
[edit]- 2-C-methylerythritol+4-phosphate at the U.S. National Library of Medicine Medical Subject Headings (MeSH)