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7-Dimethylallyltryptophan synthase

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7-dimethylallyltryptophan synthase
Identifiers
EC no.2.5.1.80
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MetaCycmetabolic pathway
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7-dimethylallyltryptophan synthase (EC 2.5.1.80, 7-DMATS) is an enzyme with systematic name dimethylallyl-diphosphate:L-tryptophan 7-dimethylallyltransferase.[1][2] This enzyme catalyses the following chemical reaction:

dimethylallyl diphosphate + L-tryptophan diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan

This enzyme is more flexible towards the aromatic substrate than EC 2.5.1.34 (4-dimethylallyltryptophan synthase).

References

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  1. ^ Kremer A, Li SM (July 2008). "Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives". Applied Microbiology and Biotechnology. 79 (6): 951–61. doi:10.1007/s00253-008-1505-3. PMID 18481055.
  2. ^ Kremer A, Westrich L, Li SM (October 2007). "A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization". Microbiology. 153 (Pt 10): 3409–16. doi:10.1099/mic.0.2007/009019-0. PMID 17906140.
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