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Aglaia

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Aglaia
Aglaia roxburghiana
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Sapindales
Family: Meliaceae
Subfamily: Melioideae
Genus: Aglaia
Lour.
Synonyms[1]
List
    • Aglaiopsis Miq.
    • Amoora Roxb.
    • Camunium Roxb.
    • Euphora Griff.
    • Hearnia F.Muell.
    • Lepidaglaia Pierre
    • Merostela Pierre
    • Nialel Adans.
    • Nimmoia Wight
    • Oraoma Turcz.

Aglaia is a genus of 121 recognised species of woody dioecious[2] trees in the mahogany family Meliaceae. They occur in the subtropical and tropical forests of Southeast Asia, northern Australia and the Pacific.[not verified in body]

Some species are important timber trees; others have scented flowers, or medicinal properties (the edible fruits duku or langsat have now been placed in the genus Lansium). Many have complex biological relationships with their dispersal agents.[not verified in body]

Phytochemistry

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Species in the genus Aglaia synthesize a unique class of highly bioactive chemical compounds known as flavaglines. Over 50 unique compounds of this class have been described so far, including rocaglamide, aglafoline, silvestrol, pannellin, episilvestrol, and ponapensin.[3][4][5][6][7] They are known for their anti-cancer, anti-fungal, anti-inflammatory and insecticidal properties. Several of these compounds have been shown to be exceptional therapeutic agents for cancer chemotherapy, however further research is needed to develop medicines.[3]

Species

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As of 9 April 2024, there are 121 species are accepted by Plants of the World Online,[1] as follows:

References

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  1. ^ a b "Aglaia Lour". Plants of the World Online. Royal Botanic Gardens, Kew. 2024. Retrieved 9 April 2024.
  2. ^ "Aglaia in Flora of China @ efloras.org". Flora of China. Retrieved 2021-08-26.
  3. ^ a b Kim, Soyoung; Salim, Angela; Swanson, Steven; Douglas Kinghorn, A. (2006-07-01). "Potential of Cyclopenta[b]benzofurans from Aglaia Species in Cancer Chemotherapy". Anti-Cancer Agents in Medicinal Chemistry. 6 (4): 319–345. doi:10.2174/187152006777698123. ISSN 1871-5206. PMID 16842234.
  4. ^ Ribeiro, Nigel; Thuaud, Frédéric; Nebigil, Canan; Désaubry, Laurent (March 2012). "Recent advances in the biology and chemistry of the flavaglines". Bioorganic & Medicinal Chemistry. 20 (6): 1857–1864. doi:10.1016/j.bmc.2011.10.048. ISSN 0968-0896. PMID 22071525.
  5. ^ Hwang, Bang Yeon; Su, Bao-Ning; Chai, Heebyung; Mi, Qiuwen; Kardono, Leonardus B. S.; Afriastini, Johar J.; Riswan, Soedarsono; Santarsiero, Bernard D.; Mesecar, Andrew D.; Wild, Robert; Fairchild, Craig R. (May 2004). "Silvestrol and Episilvestrol, Potential Anticancer Rocaglate Derivatives from Aglaia silvestris". The Journal of Organic Chemistry. 69 (10): 3350–3358. doi:10.1021/jo040120f. ISSN 0022-3263. PMID 15132542.
  6. ^ Brader, G.; Vajrodaya, S.; Greger, H.; Bacher, M.; Kalchhauser, H.; Hofer, O. (December 1998). "Bisamides, Lignans, Triterpenes, and Insecticidal Cyclopenta[b]benzofurans from AglaiaSpecies1". Journal of Natural Products. 61 (12): 1482–1490. doi:10.1021/np9801965. ISSN 0163-3864. PMID 9868148.
  7. ^ Salim, Angela A.; Pawlus, Alison D.; Chai, Hee-Byung; Farnsworth, Norman R.; Douglas Kinghorn, A.; Carcache-Blanco, Esperanza J. (January 2007). "Ponapensin, a cyclopenta[bc]benzopyran with potent NF-κB inhibitory activity from Aglaia ponapensis". Bioorganic & Medicinal Chemistry Letters. 17 (1): 109–112. doi:10.1016/j.bmcl.2006.09.084. ISSN 0960-894X. PMC 2786496. PMID 17055270.
[edit]
  • Pannell, C.M. (1992). A taxonomic monograph of the genus Aglaia Lour. (Meliaceae). Kew Bulletin Additional Series. Vol. XV1. London: HMSO. ISBN 978-0-11-250067-4.
  • Pannell, C.M. (1997). Dranseld, J.; et al. (eds.). Solving problems in the taxonomy of Aglaia (Meliaceae): functional syndromes and the biological monograph. Pl. Div. Mal. Vol. III. pp. 163–170.
  • Satasook, C.; Isman, M.B.; Ishibashi, F.; Medbury, S.; Wiriyachitra, P.; Towers, G.H.N. (1994), "Insecticidal bioactivity of crude extracts of Aglaia species (Meliaceae)", Biochemical Systematics and Ecology, 22 (2): 121–7, Bibcode:1994BioSE..22..121S, doi:10.1016/0305-1978(94)90002-7
  • "Aglaia Lour". Atlas of Living Australia.