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CACNA1B

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CACNA1B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCACNA1B, BIII, CACNL1A5, CACNN, Cav2.2, DYT23, calcium voltage-gated channel subunit alpha1 B, NEDNEH
External IDsOMIM: 601012; MGI: 88296; HomoloGene: 20184; GeneCards: CACNA1B; OMA:CACNA1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000718
NM_001243812

NM_001042528
NM_007579

RefSeq (protein)

NP_000709
NP_001230741

NP_001035993
NP_031605

Location (UCSC)Chr 9: 137.88 – 138.12 MbChr 2: 24.49 – 24.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The voltage-dependent N-type calcium channel subunit alpha-1B is a protein that in humans is encoded by the CACNA1B gene.[5][6][7] The α1B protein, together with β and α2δ subunits forms N-type calcium channel (Cav2.2 channel).[8] It is a R-type calcium channel.[citation needed]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000148408Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004113Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit".
  6. ^ Diriong S, Lory P, Williams ME, Ellis SB, Harpold MM, Taviaux S (December 1995). "Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits". Genomics. 30 (3): 605–609. doi:10.1006/geno.1995.1284. PMID 8825650.
  7. ^ Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (December 2005). "International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacological Reviews. 57 (4): 411–425. doi:10.1124/pr.57.4.5. PMID 16382099. S2CID 10386627.
  8. ^ Heyes S, Pratt WS, Rees E, Dahimene S, Ferron L, Owen MJ, et al. (November 2015). "Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders". Progress in Neurobiology. 134: 36–54. doi:10.1016/j.pneurobio.2015.09.002. PMC 4658333. PMID 26386135.

Further reading

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