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Cytochrome b5, type A

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(Redirected from CYB5A)
CYB5A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCYB5A, CYB5, MCB5, Cytochrome b5, type A, cytochrome b5 type A, METAG
External IDsOMIM: 613218; MGI: 1926952; HomoloGene: 41475; GeneCards: CYB5A; OMA:CYB5A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001190807
NM_001914
NM_148923

NM_025797
NM_001348159

RefSeq (protein)

NP_001177736
NP_001905
NP_683725

NP_080073
NP_001335088

Location (UCSC)Chr 18: 74.25 – 74.29 MbChr 18: 84.86 – 84.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cytochrome b5, form A (gene name CYB5A), is a human microsomal cytochrome b5.[5]

Cytochrome b5 is a membrane bound hemoprotein which functions as an electron carrier for several membrane bound oxygenases. It has two isoforms produced by alternative splicing. Isoform 1 is bound to the cytoplasmic side of the endoplasmic reticulum. It has a C-terminal transmembrane alpha-helix. Isoform 2 was found in cytoplasm. Defects in CYB5A are the cause of type IV hereditary methemoglobinemia.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166347Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024646Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CYB5A Cytochrome b5, form A".

Further reading

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