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Protein-coding gene in humans
Neuron-specific vesicular protein calcyon is a protein that in humans is encoded by the CALY gene .[ 5] [ 6] Calcyon .
The protein encoded by this gene is a type II single transmembrane protein . It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors . The encoded protein interacts with dopamine receptor D1 and may interact with other DA receptor subtypes and/or GPCRs .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000130643 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025468 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Heijtz RD, Alexeyenko A, Castellanos FX (July 2007). "Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD" . Behavioral and Brain Functions . 3 (1): 33. doi :10.1186/1744-9081-3-33 PMC 1949817 PMID 17623072 . ^ a b "CALY calcyon neuron specific vesicular protein [ Homo sapiens (human) ]" .^ Kim JH, Jung HG, Kim A, Shim HS, Hyeon SJ, Lee YS, et al. (March 2021). "Hevin-calcyon interaction promotes synaptic reorganization after brain injury" . Cell Death and Differentiation . 28 (9): 2571–2588. doi :10.1038/s41418-021-00772-5 PMC 8408247 PMID 33753902 .
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