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RB1CC1

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(Redirected from FIP200)
RB1CC1
Identifiers
AliasesRB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1
External IDsOMIM: 606837; MGI: 1341850; HomoloGene: 7659; GeneCards: RB1CC1; OMA:RB1CC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001083617
NM_014781

NM_009826

RefSeq (protein)

NP_001077086
NP_055596

NP_033956

Location (UCSC)Chr 8: 52.62 – 52.75 MbChr 1: 6.21 – 6.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.[5][6][7][8]

Interactions

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RB1CC1 has been shown to interact with PTK2B,[9] ASK1[10] and PTK2.[9]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000023287Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025907Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y (Feb 2002). "Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells". Oncogene. 21 (8): 1295–8. doi:10.1038/sj.onc.1205171. PMID 11850849. S2CID 1446211.
  6. ^ Maucuer A, Camonis JH, Sobel A (Apr 1995). "Stathmin interaction with a putative kinase and coiled-coil-forming protein domains". Proceedings of the National Academy of Sciences of the United States of America. 92 (8): 3100–4. Bibcode:1995PNAS...92.3100M. doi:10.1073/pnas.92.8.3100. PMC 42112. PMID 7724523.
  7. ^ Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N (May 2008). "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells". The Journal of Cell Biology. 181 (3): 497–510. doi:10.1083/jcb.200712064. PMC 2364687. PMID 18443221.
  8. ^ "Entrez Gene: RB1CC1 RB1-inducible coiled-coil 1".
  9. ^ a b Ueda H, Abbi S, Zheng C, Guan JL (Apr 2000). "Suppression of Pyk2 kinase and cellular activities by FIP200". The Journal of Cell Biology. 149 (2): 423–30. doi:10.1083/jcb.149.2.423. PMC 2175150. PMID 10769033.
  10. ^ Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL (Oct 2006). "Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways". The Journal of Cell Biology. 175 (1): 121–33. doi:10.1083/jcb.200604129. PMC 2064504. PMID 17015619.

Further reading

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