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File:Cytotoxic T Cell Destroying Infected Cell.svg

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English: When a cell is infected, the helper T Cells direct the cytotoxic T Cells to destroy the cell. Using small HMC’s located all over the cell which contain fragments of a pathogen, the infected cell is detected and latched onto by the T Cell. Perforin breaks the membrane and the lymphotoxin flows in and kills the cell.

1) One cell is infected by a virus. The Histocompatibility Complexes located all around the cell have parts of the virus on them, allowing the T Cell to detect the infected cell.

2) A) Pathogen B) T Cell Receptor Complex (TCR) C) T Cell D) Lymphotoxin E) Lymphokine F) Major Histocompatibility Complex (MHC)

3) G) Perforin H) CD8

4) Antigen is destroyed and cell components flow out through the now porous membrane.

Ignore changes in cell size. MHCs are located all over the cell. One was enlarged for simplicity in this diagram.
Date
Source Own work
Author SpencerAC

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2 June 2016

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