File:Heterotetramer of DNMTs 3A2 and 3B3 and its interactions with nucleosome and linker DNA.jpg
Size of this preview: 800 × 576 pixels. Other resolutions: 320 × 230 pixels | 640 × 461 pixels | 1,024 × 737 pixels | 1,280 × 921 pixels | 2,110 × 1,519 pixels.
Original file (2,110 × 1,519 pixels, file size: 608 KB, MIME type: image/jpeg)
 | This is a file from the Wikimedia Commons. Information from its description page there is shown below. Commons is a freely licensed media file repository. You can help. |
Summary
| Description |
English: The DNA methylating enzyme DNMT3A2, transcribed from an alternate promoter of DNMT3A1, can be active in vivo when complexed with the accessory protein DNMT3B3 in a heterotetramer structure shown here. As shown, the proximal 3B3 accessory protein interacts with a histone in the nucleosome and positions the 3A3 catalytic region of the distal 3A3 enzyme to methylate CpG sites in the adjacent linker DNA. |
| Date | |
| Source | Own work |
| Author | MethylC5 |
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:20, 31 August 2023 | | 2,110 × 1,519 (608 KB) | MethylC5 | Uploaded own work with UploadWizard |
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):
