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File:Hormones estradiol, progesterone, LH and FSH during menstrual cycle.svg

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Summary

Description
English: Reference ranges for the blood content of the hormones estradiol (the main estrogen), progesterone, follicle-stimulating hormone and luteinizing hormone during the menstrual cycle.


Interpretation

The time scale starts with the beginning (or "onset") of (last) menstrual period (LMP), given as day number. Day number 1 corresponds to 0 to 0.99 days from LMP, and Day number 2 corresponds to 1.00 to 1.99 days from LMP and so forth. The time scale ends at whatever is the actual next menstruation, which marks the beginning of the next cycle, which is equivalent to starting all over again from the beginning of the time scale.

  • Inter-cycle (also called within-woman or intrawoman) variability for ovulation and next menstruation are the 95% prediction intervals for the timing of these events in any single woman, assuming an inter-cycle average duration that is equal to population average.
  • Inter-woman variability for ovulation and next menstruation are the 95% prediction intervals for the timing of these events in the overall population.

Hormone levels represent usual ones, not necessarily related to what is healthy. Hormone ranges vary between cases at the same biological stage of the menstrual cycle. Furthermore, the actual timing (usually given in day numbers from mentruation) of that biological stage varies, both between cycles of any single woman (inter-cycle) and between somen (inter-woman). Therefore, the appropriate ranges to use depend on how certain the actual biological stage can be estimated at any time.

  • The ranges denoted By biological stage are the 90% prediction intervals for hormone levels for women at the same biological stage. These reference ranges may be used in closely monitored menstrual cycles in regard to other markers of its biological progression, with the time scale being compressed or stretched to how much faster or slower, respectively, the cycle progresses compared to an average cycle. In the luteal phase, a known time of ovulation is sufficient to use these ranges.
  • The ranges denoted Inter-cycle variability (also called within-woman or intrawoman variability) are the up to 95% prediction intervals for any single woman, assuming an inter-cycle average duration that is equal to population average. These ranges are more appropriate to use in non-monitored cycles with only the beginning of menstruation known, but where the woman accurately knowing her average cycle lengths and time of ovulation, and that they are somewhat averagely regular, with the time scale being compressed or stretched to how much a woman's average cycle length is shorter or longer, respectively, than the average of the population.
  • The ranges denoted Inter-woman variability are the up to 95% prediction intervals for hormone levels in the overall population. These ranges are more appropriate in non-monitored cycles, where the average cycle lengths and time of ovulation are unknown, but only the beginning of menstruation is given.

Derivation

See source article:

Date
Source

Own work. Source article:

Author Mikael Häggström
Other versions

Derivative works of this file:  Hormones estradiol, progesterone, LH and FSH during menstrual cycle pt.svg

.png-format

Licensing

Public domain I, the copyright holder of this work, release this work into the public domain. This applies worldwide.
In some countries this may not be legally possible; if so:
I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.

Derivatives

Estradiol during menstrual cycle.png
Progesterone during menstrual cycle.png
Follice-stimulating hormone (FSH) during menstrual cycle.png
Luteinizing hormone (LH) during menstrual cycle.png

Captions

Graphs of the reference concentrations of hormones that regulate the menstrual cycle.

Items portrayed in this file

depicts

22 January 2011

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current14:54, 22 January 2011Thumbnail for version as of 14:54, 22 January 2011831 × 1,635 (412 KB)Mikael HäggströmUpdate
17:24, 9 January 2011Thumbnail for version as of 17:24, 9 January 2011654 × 624 (115 KB)Mikael HäggströmCorrected prediction intervals
10:18, 9 January 2011Thumbnail for version as of 10:18, 9 January 2011654 × 624 (111 KB)Mikael Häggströmexpanded lh and fsh boxes
10:15, 9 January 2011Thumbnail for version as of 10:15, 9 January 2011654 × 624 (111 KB)Mikael Häggström{{Information |Description={{en|1=g}} |Source={{own}} |Author=Mikael Häggström |Date=2011-01-09 |Permission= |other_versions= }}

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