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English: Schematic Examples of CNS Structural Changes. Red circles signify decreased gray matter density relative to controls. A. Subjects with chronic back pain show decreases in gray matter density in bilateral dorsolateral prefrontal cortex (DLPFC) and right anterior thalamus (adapted from [25]). B. Patients with fibromyalgia show decreases in cingulate cortex (CC), medial prefrontal cortex (Med. PFC), parahippocampal gyrus (PHG) and insula (adapted from [27]). 3-D surface renderings were created using Freesurfer. Borsook et al. Molecular Pain 2007 3:25 doi:10.1186/1744-8069-3-25
Français : Schéma CNS ; Exemples de changements structurels. Les ronds rouges pointent une diminution de la densité de matière grise par rapport à un sujet-témoin normal. A. Sujets présentant une douleur dorsale chronique montrent une diminution de la densité de matière grise dans le cortex préfrontal dorsolatéral bilatéral (DLPFC) et dans le thalamus antérieur droit (adapté de [25]). B. Les patients avec fibromyalgie montrant des diminutions dans le cortex cingulaire (CC), le cortex préfrontal médian (Med. PFC), le gyrus para-hippocampique (PHG) et l'insula (adapté de [27]). des rendus 3-D de surface ont été créés à l'aide de Freesurfer. Borsook et al. Molecular Pain 2007 3:25 doi: 10.1186/1744-8069-3-25
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Source Neuroimaging revolutionizes therapeutic approaches to chronic pain
Author Borsook D, Moulton EA, Schmidt KF, Becerra LR.
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