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Gamma-glutamyltransferase 7

From Wikipedia, the free encyclopedia
(Redirected from GGTL3)
GGT7
Identifiers
AliasesGGT7, D20S101, GGT4, GGTL3, GGTL5, dJ18C9.2, gamma-glutamyltransferase 7
External IDsOMIM: 612342; MGI: 1913385; HomoloGene: 70866; GeneCards: GGT7; OMA:GGT7 - orthologs
EC number3.4.19.13
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178026
NM_001351702
NM_178025

NM_144786
NM_001362898
NM_001362900

RefSeq (protein)

NP_821158
NP_001338631
NP_821158.2

NP_659035
NP_001349827
NP_001349829

Location (UCSC)Chr 20: 34.84 – 34.87 MbChr 2: 155.49 – 155.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-glutamyltransferase 7 is an enzyme that in humans is encoded by the GGT7 gene.[5][6][7]

Function

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Gamma-glutamyltransferase is a membrane-associated protein involved in both glutathione metabolism and the transpeptidation of amino acids. Changes in gamma-glutamyltransferase activity may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene is similar in sequence to gamma-glutamyltransferase, but its function is unknown.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000131067Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027603Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Figlewicz DA, Delattre O, Guellaen G, Krizus A, Thomas G, Zucman J, Rouleau GA (August 1993). "Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes". Genomics. 17 (2): 299–305. doi:10.1006/geno.1993.1325. PMID 8104871.
  6. ^ Heisterkamp N, Groffen J, Warburton D, Sneddon TP (May 2008). "The human gamma-glutamyltransferase gene family". Human Genetics. 123 (4): 321–32. doi:10.1007/s00439-008-0487-7. PMID 18357469. S2CID 15916758.
  7. ^ a b "Entrez Gene: GGTL3 gamma-glutamyltransferase-like 3".

Further reading

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