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21S rRNA (uridine2791-2'-O)-methyltransferase

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(Redirected from MRM2 (gene))
21S rRNA (uridine2791-2'-O)-methyltransferase
Identifiers
EC no.2.1.1.168
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

21S rRNA (uridine2791-2'-O)-methyltransferase (EC 2.1.1.168, MRM2 (gene), mitochondrial 21S rRNA methyltransferase, mitochondrial rRNA MTase 2) is an enzyme with systematic name S-adenosyl-L-methionine:21S rRNA (uridine2791-2'-O-)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uridine2791 in 21S rRNA S-adenosyl-L-homocysteine + 2'-O-methyluridine2791 in 21S rRNA

The enzyme catalyses the methylation of uridine2791 of mitochondrial 21S rRNA.

References

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  1. ^ Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C (March 2002). "MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase". The EMBO Journal. 21 (5): 1139–47. doi:10.1093/emboj/21.5.1139. PMC 125888. PMID 11867542.
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