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Proliferating trichilemmal cyst

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Proliferating trichilemmal cyst
Other namesPilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor
Proliferating tricholemmal (pilar) cyst
SpecialtyDermatology

Proliferating trichilemmal cysts (also known as a pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor)[1] is a cutaneous condition, characterized by proliferations of squamous cells forming scroll-like structures.[1][2]: 678 

Signs and symptoms

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The tumors, which are typically found in regions like the scalp with a high density of hair follicles, can be solid or solid cystic. Proliferating trichilemmal cyst frequently manifests clinically as a subcutaneous nodule that gradually grows into a big nodular mass. Rapid growth in some cases may be a sign of malignant development into cancer.[3]

Diagnosis

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Histologically, Proliferating trichilemmal cysts are distinguished by trichilemmal keratinization, which is the sudden change from nucleated epithelium to anucleated keratinized cells without a granular layer.[4] The differential diagnosis include trichilemmal cyst and Turban tumor.[5]

Treatment

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Surgical excision is the treatment of choice for proliferating trichilemmal cysts.[4]

Epidemiology

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Proliferating trichilemmal cysts make up 0.1% of all skin tumors.[4] Most patients with these tumors are older women, and 90% of patients with these lesions appear on the scalp.[6]

See also

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References

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  1. ^ a b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  3. ^ Valerio, Ediel; Parro, Fernando Henrique Sgarbi; Macedo, Mariana Petaccia de; Pinto, Clovis Antonio Lopes (2019). "Proliferating trichilemmal cyst with clinical, radiological, macroscopic, and microscopic correlation". Anais Brasileiros de Dermatologia. 94 (4). FapUNIFESP (SciELO): 452–454. doi:10.1590/abd1806-4841.20198199. ISSN 1806-4841. PMC 7007035. PMID 31644620.
  4. ^ a b c Capurso-García, Marino Antonio; Bautista-Piña, Verónica; Pomerantz, Alan; Galnares-Olalde, Javier Andrés; Blachman-Braun, Ruben; Rodríguez-Rodríguez, Sergio; Goldberg-Murow, Monica (2016). "Atypical Proliferating Trichilemmal Cyst with Malignant Breast Skin Transformation: A Case Report and Review of the Literature". Case Reports in Oncological Medicine. 2016. Hindawi Limited: 1–4. doi:10.1155/2016/7481569. ISSN 2090-6706. PMC 4923530. PMID 27403361.
  5. ^ Chang, S.J.; Sims, J.; Murtagh, F.R.; McCaffrey, J.C.; Messina, J.L. (2006-03-01). "Proliferating Trichilemmal Cysts of the Scalp on CT". American Journal of Neuroradiology. 27 (3): 712–714. ISSN 0195-6108. PMC 7976987. PMID 16552022. Retrieved 2024-05-11.
  6. ^ Deshmukh, BhaktiD; Kulkarni, MedhaP; Momin, YasminA; Sulhyan, KalpanaR (2014). "Malignant proliferating trichilemmal tumor: A case report and review of literature". Journal of Cancer Research and Therapeutics. 10 (3): 767. doi:10.4103/0973-1482.136036. ISSN 0973-1482. PMID 25313781.

Further reading

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