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Neutrophilic dermatosis of the dorsal hands

From Wikipedia, the free encyclopedia
Neutrophilic dermatosis of the dorsal hands
Other namesPustular vasculitis of the dorsal hands
SpecialtyDermatology

Neutrophilic dermatosis of the dorsal hands (NDDH) is a skin condition that presents with edematous pustular or ulcerative nodules or plaques localized to the dorsal hands.[1]: 146 [2]

Signs and symptoms

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Neutrophilic dermatosis of the dorsal hands is characterized by bullae, pustules, and delicate erythematous plaques on the hands' dorsa.[3]

Causes

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Neutrophilic dermatosis of the dorsal hands is often associated with other conditions. Hematological disorders such as myelodysplastic syndrome and plasma cell dyscrasias are common.[3]

Diagnosis

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The histopathology of NDDH lesions shows a dense neutrophil infiltrate in the dermis, which is typically linked to leukocytoclastic debris and subepidermal edema.[4]

Treatment

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Systemic corticosteroids are the main method of treatment.[3]

See also

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References

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  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ^ Dicaudo, David J.; Connolly, Suzanne M. (2002). "Neutrophilic Dermatosis (Pustular Vasculitis) of the Dorsal Hands". Archives of Dermatology. 138 (3): 361–365. doi:10.1001/archderm.138.3.361. PMID 11902987.
  3. ^ a b c Micallef, Daniel; Bonnici, Maria; Pisani, David; Boffa, Michael J. (2023). "Neutrophilic dermatosis of the dorsal hands: A review of 123 cases". Journal of the American Academy of Dermatology. 88 (6). Elsevier BV: 1338–1344. doi:10.1016/j.jaad.2019.08.070. ISSN 0190-9622. PMID 31499154. S2CID 202412220.
  4. ^ Kaur, S; Gupta, D; Garg, B; Sood, N (2015). "Neutrophilic dermatosis of dorsal hands". Indian Dermatology Online Journal. 6 (1). Medknow: 42–45. doi:10.4103/2229-5178.148940. ISSN 2229-5178. PMC 4314889. PMID 25657918.

Further reading

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  • DEL POZO, Jesús; SACRISTÁN, Felipe; MARTÍNEZ, Walter; PARADELA, Sabela; FERNÁNDEZ-JORGE, Beatriz; FONSECA, Eduardo (March 9, 2007). "Neutrophilic dermatosis of the hands: Presentation of eight cases and review of the literature". The Journal of Dermatology. 34 (4). Wiley: 243–247. doi:10.1111/j.1346-8138.2007.00261.x. ISSN 0385-2407. PMID 17352721. S2CID 34488900.
  • Galaria, Noreen A.; Junkins-Hopkins, Jacqueline M.; Kligman, Douglas; James, William D. (2000). "Neutrophilic dermatosis of the dorsal hands: Pustular vasculitis revisited". Journal of the American Academy of Dermatology. 43 (5). Elsevier BV: 870–874. doi:10.1067/mjd.2000.109286. ISSN 0190-9622. PMID 11050599.
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