Talk:Management of Tourette syndrome

Prolactin and risperidone

Hi, Wuffuwwuf. To help you out with this series of edits:

Broken citations

Here is the text before your edit:

Aripiprazole and risperidone are likely to lead to weight gain and sedation or fatigue; haloperidol may increase prolactin levels; tiapride may produce sleep disturbances and tiredness; and clonidine may produce sedation. Risperidone and haloperidol may produce extrapyramidal symptoms.[5]

All of that text is cited to [5]. Here is the text after your edit:

Aripiprazole and risperidone are likely to lead to weight gain and sedation or fatigue; haloperidol and risperidone[37] may increase prolactin levels; tiapride may produce sleep disturbances and tiredness; and clonidine may produce sedation. Risperidone and haloperidol may produce extrapyramidal symptoms.[5]

This makes the new citation (37) the source for everything before it, which it is not. The edit has broken the source-to-text integrity. Is 37 also sourcing weight gain, sedation and fatigue for airpiprazole and prolactin for haldol? Adding new information like this mid-sentence requires rewriting the entire paragraph to make sure that the new citation is added where it verifies everything preceding it, since the last citation. Also, neither your new or old source is adequate or fully formatted, providing the needed information for verification.

Further, once you have made a bold addition and your work has once been removed, it is customary to discuss before re-adding. Have a look at WP:MEDRS, WP:MEDDATE and WP:BRD. Please hold off on further edits to this section; Pringsheim 2019 did not indicate that risperidone was a problem-- I will do a new search to see if there is any new information, and repair the paragraph accordingly. Regards, SandyGeorgia (Talk) 19:47, 3 April 2022 (UTC)

Ok, sorry, I understand. Thanks! Wuffuwwuf (talk) 19:48, 3 April 2022 (UTC)

Actually, from the way you made this edit, I cannot tell what you are trying to add. Could you please clarify? Then I can determine whether there are any new WP:MEDDATE, WP:MEDRS sources. SandyGeorgia (Talk) 19:49, 3 April 2022 (UTC)

Only the fact that risperidone also causes hyperprolactinemia. I also found this https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007722/ article which says that. Wuffuwwuf (talk) 19:57, 3 April 2022 (UTC)

Gotcha ... PMID 32892632

• Iasevoli F, Barone A, Buonaguro EF, Vellucci L, de Bartolomeis A (November 2020). "Safety and tolerability of antipsychotic agents in neurodevelopmental disorders: a systematic review". Expert Opin Drug Saf. 19 (11): 1419–1444. doi:10.1080/14740338.2020.1820985. PMID 32892632.

is a newer and better source (try to avoid dated sources in medical content), and is specific to neurodevelopmental disorders including TS.

Also, a better way to discuss sources on talk is use the built-in PMID link like this:

• Typing {{pmid|29955468}} yields PMID 29955468

and plugging a PMID in to

• this tool

will give you a full and correctly formatted citation. I will go fix that now, using Iasevoli 2020; you can follow my edits to see how I rejig the paragraph to maintain source-to-text integrity. SandyGeorgia (Talk) 20:07, 3 April 2022 (UTC)

Ok, I will. Thanks for the help! Wuffuwwuf (talk) 20:14, 3 April 2022 (UTC)

All done; did you follow? See how that ends up? A new sentence about haldol and risperdal, with the new info and citations, the old stuff still attched to Pringsheim 2019, so it's clear what's what. Best regards, happy editing! SandyGeorgia (Talk) 20:17, 3 April 2022 (UTC)