Tengion

Tengion, Inc.
Company type	Public
Traded as	Expert Market: TNGNQ
Industry	Biotechnology
Founded	2003
Headquarters	Winston-Salem, North Carolina, United States
Key people	David I. Scheer ; (Chairman) ; John L. Miclot ; (Chief Executive Officer, President, and Director) ; A. Brian Davis ; (Chief Financial Officer, Principal Accounting Officer) ; Timothy A. Bertram DVM, PhD (Chief Scientific Officer) (Dec 31, 2012)
Number of employees	25
Website	www.tengion.com [dead link]

Tengion, Inc. is an American development-stage regenerative medicine company founded in 2003 with financing from J&J Development Corporation, HealthCap and Oak Investment Partners, which is headquartered in Winston-Salem, North Carolina.^[1] Its goals are discovering, developing, manufacturing and commercializing a range of replacement organs and tissues, or neo-organs and neo-tissues, to address unmet medical needs in urologic, renal, gastrointestinal, and vascular diseases and disorders. The company creates these human neo-organs from a patient’s own cells or autologous cells, in conjunction with its Organ Regeneration Platform.

The company declared Chapter 7 bankruptcy in December 2014, and it, along with its assets and tissue engineering samples, have been bought back by its creditors and former executives as of March 2015. The purchase was expedited, so that time-sensitive research can continue.^[2]

History[edit]

Founded in 2003 and formerly headquartered in East Norriton Township, Pennsylvania before moving to Winston-Salem, North Carolina in 2012,^[3] Tengion went public in 2010, after its stock has been approved for listing on the NASDAQ, through a $26 million IPO to help advance its research and development activities.^[4] Some of the groundbreaking regenerative medicine technologies of Dr. Anthony Atala, director of the Wake Forest Institute for Regenerative Medicine, were the core from where those research and development activities developed.^[5]^[6]

On September 4, 2012, Tengion received a notice from NASDAQ stating that the company had not regained compliance with NASDAQ Listing Rule 5550(b)(1) and that its common stock would cease trading on the NASDAQ Capital Market effective on September 6, 2012, and would begin trading on the OTCQB tier of the OTC Marketplace.^[7] The company was bought by former executives and creditors after declaring bankruptcy in 2014.^[2]

Products[edit]

All current Tengion's regenerative medicine product candidates are investigational and will not be commercially available until the completion of clinical trials and the review and approval of associated marketing applications by the Food and Drug Administration.

Product candidates in clinical development[edit]

Its most advanced candidate is the Neo-Urinary Conduit. A Phase I clinical trial of the Tengion Neo-Urinary Conduit was completed in some health care institutions, in patients with bladder cancer who require a total cystectomy. The trial ended in December 2014, however information on the results has not yet been made publicly available.^[8]

References[edit]

^ Health Care Sector Wrap Archived 2012-08-18 at the Wayback Machine, FOX BUSINESS (August 14, 2012)
^ ^a ^b Craver, Richard (March 6, 2015). "Bankruptcy Court approves offer to buy Tengion". Winston-Salem Journal. Retrieved June 3, 2024.
^ Tengion completes move to Winston-Salem Archived 2012-01-20 at the Wayback Machine, Winston-Salem Journal (January 05, 2012)
^ Tengion Inc., Hoover's
^ Matt Evans, Tengion plans IPO around Atala’s groundbreaking work, The Business Journal (February 15, 2010)
^ Anthony Atala: at the cutting edge of regenerative surgery, The Lancet (15 October 2011)
^ Tengion Common Stock to Begin Trading on The OTCQB™ Tier of the OTC Marketplace on September 6, 2012^{[permanent dead link]}, heraldonline.com (September 5, 2012)
^ Tengion. Incontinent Urinary Diversion Using an Autologous Neo-Urinary Conduit. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2016 April 10th]. Available from: https://clinicaltrials.gov/ct2/show/NCT01087697 NLM Identifier: NCT01087697.

[1] Health Care Sector Wrap Archived 2012-08-18 at the Wayback Machine, FOX BUSINESS (August 14, 2012)

[ws2014-2] Craver, Richard (March 6, 2015). "Bankruptcy Court approves offer to buy Tengion". Winston-Salem Journal. Retrieved June 3, 2024.

[3] Tengion completes move to Winston-Salem Archived 2012-01-20 at the Wayback Machine, Winston-Salem Journal (January 05, 2012)

[4] Tengion Inc., Hoover's

[5] Matt Evans, Tengion plans IPO around Atala’s groundbreaking work, The Business Journal (February 15, 2010)

[6] Anthony Atala: at the cutting edge of regenerative surgery, The Lancet (15 October 2011)

[7] Tengion Common Stock to Begin Trading on The OTCQB™ Tier of the OTC Marketplace on September 6, 2012^{[permanent dead link]}, heraldonline.com (September 5, 2012)

[8] Tengion. Incontinent Urinary Diversion Using an Autologous Neo-Urinary Conduit. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2016 April 10th]. Available from: https://clinicaltrials.gov/ct2/show/NCT01087697 NLM Identifier: NCT01087697.

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