BCAS2

BCAS2
Identifiers
Aliases	BCAS2, DAM1, SPF27, Snt309, breast carcinoma amplified sequence 2, pre-mRNA processing factor, BCAS2 pre-mRNA processing factor
External IDs	OMIM: 605783 MGI: 1915433 HomoloGene: 4291 GeneCards: BCAS2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	114,581,629 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	103,086,482 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; palpebral conjunctiva; ; pons; ; endothelial cell; ; islet of Langerhans; ; parietal pleura; ; hair follicle; ; biceps brachii; ; orbitofrontal cortex;
	Top expressed in
	maxillary prominence; ; endocardial cushion; ; superior cervical ganglion; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus; ; atrioventricular valve; ; somite; ; arcuate nucleus; ; mammillary body; ; lateral hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	DNA replication factor A complex; catalytic step 2 spliceosome; spliceosomal complex; nucleolus; precatalytic spliceosome; Prp19 complex; nucleoplasm; nucleus; centrosome; nuclear speck; U2-type catalytic step 2 spliceosome;
Biological process	RNA splicing, via transesterification reactions; mRNA processing; RNA splicing; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	10286
	68183
	ENSG00000116752
	ENSMUSG00000005687
	O75934
	Q9D287
	NM_005872
	NM_026602; NM_001356330; NM_001356331
	NP_005863
	NP_080878; NP_001343259; NP_001343260
	Wikidata
View/Edit Human	View/Edit Mouse

Pre-mRNA-splicing factor SPF27 is a protein that in humans is encoded by the BCAS2 gene.^[5]^[6]^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116752 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000005687 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M (Oct 1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex". Nat Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529. S2CID 585778.
^ Nagasaki K, Maass N, Manabe T, Hanzawa H, Tsukada T, Kikuchi K, Yamaguchi K (Aug 1999). "Identification of a novel gene, DAM1, amplified at chromosome 1p13.3-21 region in human breast cancer cell lines". Cancer Lett. 140 (1–2): 219–26. doi:10.1016/S0304-3835(99)00091-9. PMID 10403562.
^ "Entrez Gene: BCAS2 breast carcinoma amplified sequence 2".

External links[edit]

BCAS2 human gene location in the UCSC Genome Browser.
BCAS2 human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000116752 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000005687 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9731529-5] Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M (Oct 1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex". Nat Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529. S2CID 585778.

[pmid10403562-6] Nagasaki K, Maass N, Manabe T, Hanzawa H, Tsukada T, Kikuchi K, Yamaguchi K (Aug 1999). "Identification of a novel gene, DAM1, amplified at chromosome 1p13.3-21 region in human breast cancer cell lines". Cancer Lett. 140 (1–2): 219–26. doi:10.1016/S0304-3835(99)00091-9. PMID 10403562.

[entrez-7] "Entrez Gene: BCAS2 breast carcinoma amplified sequence 2".

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Further reading[edit]

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