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Bone morphogenetic protein 10

From Wikipedia, the free encyclopedia

BMP10
Identifiers
AliasesBMP10, entrez:27302, bone morphogenetic protein 10
External IDsOMIM: 608748; MGI: 1338820; HomoloGene: 7644; GeneCards: BMP10; OMA:BMP10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014482

NM_009756

RefSeq (protein)

NP_055297

NP_033886

Location (UCSC)Chr 2: 68.86 – 68.87 MbChr 6: 87.41 – 87.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Bone morphogenetic protein 10 (BMP10) is a protein that in humans is encoded by the BMP10 gene.[5][6]

BMP10 is a polypeptide belonging to the TGF-β superfamily of proteins.[6] It is a novel protein that, unlike most other BMP's, is likely to be involved in the trabeculation of the heart. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP10 is categorized as a BMP since it shares a large sequence homology with other BMP's in the TGF-β superfamily.

Further reading

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163217Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030046Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: bone morphogenetic protein 10".
  6. ^ a b Neuhaus H, Rosen V, Thies RS (February 1999). "Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily". Mech. Dev. 80 (2): 181–4. doi:10.1016/S0925-4773(98)00221-4. PMID 10072785. S2CID 15626081.
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