Bruno Conti (biologist)

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Bruno Conti
NationalityItalian American
Occupation(s)Biologist, Professor

Bruno Conti is an Italian American biologist.

Career[edit]

Conti specializes in the study of aging and age-related neurodegeneration. He a Professor at the San Diego Biomedical Research Institute,[1] an Emeritus Professor at Scripps Research,[2] and an Adjunct Professor at Stockholm University and at Yale University.[3]

Conti discovered that reducing core body temperature can extend lifespan, independent of calorie intake.[4] His team identified molecules that mediate temperature reduction during calorie restriction and found that three key longevity regulators - body temperature, calorie restriction, and the IGF-1R - are part of the same pathway.[5]

Currently, Conti is working on identifying the genetic and biochemical pathways that mediate the effects of temperature on lifespan. The goal is to find potential targets for creating "temperature mimetics" to treat aging and age-related diseases.[6][7]

References[edit]

  1. ^ "BRUNO CONTI, PH.D." San Diego Biomedical Research Institute San Diego.
  2. ^ https://www.scripps.edu/faculty/conti/
  3. ^ "Bruno Conti". Yale.edu.
  4. ^ "Can a drug mimic the life extending effects of calorie restriction?". Medical News Today. 13 September 2020.
  5. ^ "Scripps Researchers Uncover What Could Make Calorie-Restricted Diets Effective". KPBS Public Media. 8 October 2020.
  6. ^ "New Research Reveals Pathway for Anti-Aging Therapies". Scripps Research.
  7. ^ "Cool down – you may live longer". New Scientist.