Draft:Eriomin
| Submission declined on 12 December 2023 by WikiDan61 (talk). Thank you for your submission, but the subject of this article already exists in Wikipedia. You can find it and improve it at Eriocitrin instead.
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| Submission declined on 5 September 2023 by Qcne (talk). This submission appears to read more like an advertisement than an entry in an encyclopedia. Encyclopedia articles need to be written from a neutral point of view, and should refer to a range of independent, reliable, published sources, not just to materials produced by the creator of the subject being discussed. This is important so that the article can meet Wikipedia's verifiability policy and the notability of the subject can be established. If you still feel that this subject is worthy of inclusion in Wikipedia, please rewrite your submission to comply with these policies. | |
Comment: There is nothing in this draft to indicate that Eriomin is anything other than a particular brand name for the generic Eriocitrin. WikiDan61ChatMe!ReadMe!! 21:07, 12 December 2023 (UTC)
- Comment: Wikipedia articles do not have FDA disclaimers on them. This reads like the label on the back of a pharma product. Qcne (talk) 15:16, 5 September 2023 (UTC)
Eriomin is a nutraceutical extract of citrus flavonoids mainly comprised of Eriocitrin. Research has expanded the understanding of how Eriomin may impact blood glucose levels, inflammation, oxidative stress, glucagon-like peptide 1, and intestinal dysbiosis.[1][2][3][4][5]
The pharmacokinetics and biodistribution of Eriocitrin metabolites were tested in vivo. Results found that seven metabolites were widely distributed in various organs, including blood plasma, liver, pancreas, spleen, and kidney[1].
Eriomin was assessed in-vivo on oxidative stress, inflammation, and glucose and lipid metabolism in high-fat diet-fed obese mice. After eight weeks, the supplemented eriocitrin group had lower levels of glucose and blood and liver triacylglycerols (P < 0⋅05). Insulin, HOMA-IR, total cholesterol, resistin, and lipid peroxidation levels also improved. [2].
Human clinical studies investigated how Eriomin benefited glycemic control, reduced systemic inflammation and oxidative stress, reversed the prediabetic condition by 24% in evaluated study participants [3], downregulated systemic inflammation, increased glucagon-like peptide 1 [4], and attenuated prediabetes intestinal dysbiosis [5].
References[edit]
- ^ Ferreira, Paula S.; Manthey, John A.; Nery, Marina S.; Cesar, Thais B. (2021-02-17). "Pharmacokinetics and Biodistribution of Eriocitrin in Rats". Journal of Agricultural and Food Chemistry. 69 (6): 1796–1805. doi:10.1021/acs.jafc.0c04553. ISSN 0021-8561. PMID 33533607. S2CID 231789713.
- ^ Ferreira, P. S.; Manthey, J. A.; Nery, M. S.; Spolidorio, L. C.; Cesar, T. B. (2020). "Low doses of eriocitrin attenuate metabolic impairment of glucose and lipids in ongoing obesogenic diet in mice". Journal of Nutritional Science. 9: e59. doi:10.1017/jns.2020.52. ISSN 2048-6790. PMC 7801930. PMID 33489104.
- ^ Ribeiro, Carolina B.; Ramos, Fernanda M.; Manthey, John A.; Cesar, Thais B. (July 2019). "Effectiveness of Eriomin® in managing hyperglycemia and reversal of prediabetes condition: A double-blind, randomized, controlled study". Phytotherapy Research. 33 (7): 1921–1933. doi:10.1002/ptr.6386. ISSN 0951-418X. PMC 6618084. PMID 31183921.
- ^ Cesar, Thais Borges; Ramos, Fernanda Maria Manzini; Ribeiro, Carolina Barbosa (2022-11-01). "Nutraceutical Eriocitrin (Eriomin) Reduces Hyperglycemia by Increasing Glucagon-Like Peptide 1 and Downregulates Systemic Inflammation: A Crossover-Randomized Clinical Trial". Journal of Medicinal Food. 25 (11): 1050–1058. doi:10.1089/jmf.2021.0181. ISSN 1096-620X. PMC 9700344. PMID 35796695.
- ^ Ramos, Fernanda M. M.; Ribeiro, Carolina B.; Cesar, Thais B.; Milenkovic, Dragan; Cabral, Lucélia; Noronha, Melline F.; Sivieri, Katia (September 19, 2023). "Lemon flavonoids nutraceutical (Eriomin®) attenuates prediabetes intestinal dysbiosis: A double-blind randomized controlled trial". Food Science & Nutrition. 11 (11): 7283–7295. doi:10.1002/fsn3.3654. ISSN 2048-7177. PMC 10630820. PMID 37970408.