Draft:HrC Cancer Blood Test

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The HrC cancer Blood Test is a new method to provide early cancer prognosis and diagnosis.

Description[edit]

Considered as path-breaking, the new blood test is designed to pick up specific markers to show changes of how stem cells are behaving.[1] After the trial of 1000 patients, it was published Stem Cell Reviews and the science behind it was also outlined in journal Stem Cells.[2][3] The test can detect the absence of cancer or its presence.[4][5][6] It can detect about 25 types of cancer including breast, liver, ovarian, lung, leukemia, renal, bladder, prostate, pancreatic, cervical and colon.[citation needed]

The test identifies cancer, a year before tumours are formed.[7][5] It is a blood biopsy technique that shows changes in the stem cells behaviour. It could be a biggest breakthrough in cancer detection.[3]

The test uses VSEL/CSC specific bio-markers in peripheral blood. VSELs are very small embryonic-like stem cells which circulate in the blood. These stem cells led to the development of the test.[8]

Development[edit]

It is co-developed by Mumbai-based biotech firm Epigeneres and Singapore-based diagnostic company Tzar Labs in 2023.[9][10] Vinay Kumar Tripathi and family members hold majority stake in the two companies, Tzar Labs and Epigeneres Biotechnology private limited.[11]

The Mumbai-based company raised $6 Mn in a Series B funding round.[12] The test is expected to cost less than Rs.10,000.[4] Patents were filed by Tzar Labs in India, apart from US, Europe, Japan, Singapore and China.[7] The test is being introduced in UK by a Doncaster-based business headed by co-founder Steve Smith.[13] He also conducting a study in UK.[14]

References[edit]

  1. ^ Bhartiya, D; Sharma, N; Dutta, S; Kumar, P; Tripathi; Tripathi, A (April 2023). "Very Small Embryonic-Like Stem Cells Transform Into Cancer Stem Cells and Are Novel Candidates for Detecting/Monitoring Cancer by a Simple Blood Test". Stem Cells (Dayton, Ohio). 41 (4): 310–318. doi:10.1093/stmcls/sxad015. ISSN 1549-4918. PMID 36881778.
  2. ^ "Indian-Led Ground-Breaking Cancer Test Hopes To Launch This Year". NDTV.com. Retrieved 2023-07-17.
  3. ^ a b hrcadmin (2023-03-27). "Holy Grail health test to ID cancer a YEAR before tumours grow". The HrC Test. Retrieved 2023-11-13.
  4. ^ a b Datta, PT Jyothi (2023-04-15). "Epigeneres Biotech operationalise the HrC test - an early warning system that picks up cancer signals". BusinessLine. Retrieved 2024-04-14.
  5. ^ a b Tripathi, V; Bhartiya, D; Vaid, A; Chhabria, S; Sharma, N; Chand, B; Takle, V; Palahe, P; Tripathi, A (October 2021). "Quest for Pan-Cancer Diagnosis/Prognosis Ends with HrC Test Measuring Oct4A in Peripheral Blood". Stem Cell Reviews and Reports. 17 (5): 1827–1839. doi:10.1007/s12015-021-10167-1. ISSN 2629-3277. PMID 33954878.
  6. ^ Video | Test For Early Cancer Detection Now In India. Retrieved 2024-04-14 – via www.ndtv.com.
  7. ^ a b Priyan, Vishnu (2021-05-10). "Start-up Tzar Labs develops blood test for cancer detection". Medical Device Network. Retrieved 2024-04-14.
  8. ^ "How a Mumbai family's research can help detect cancer early". The Week. Retrieved 2024-04-20.
  9. ^ Stoneman, Justin (2023-03-25). "'Holy Grail' health test to ID cancer a YEAR before tumours grow". Express.co.uk. Retrieved 2023-04-20.
  10. ^ "Watch | A Breakthrough Moment? Tzar Labs Develops Blood-Based Test to Detect Cancer". The Wire. Retrieved 2024-04-20.
  11. ^ KK, Sruthijith (2021-05-07). "Indian biotech startup reports early cancer detection breakthrough". mint. Retrieved 2024-04-14.
  12. ^ Inc42, Team (2022-01-19). "Early Cancer-Detection Startup Epigeneres Biotech Bags $6 Mn". Inc42 Media. Retrieved 2023-11-13.{{cite web}}: CS1 maint: numeric names: authors list (link)
  13. ^ "New Blood Test Detects 25 Different Types of Cancer". Retrieved 2024-04-14.
  14. ^ "Search - NIHR Funding and Awards". fundingawards.nihr.ac.uk. Retrieved 2024-04-14.