Draft:Ian Charles
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Ian Charles OBE is Director of the Quadram Institute in Norwich, UK. The Institute combines Quadram Institute Bioscience (the former Biotechnology and Biological Sciences Research Council (BBSRC) Institute of Food Research) and the endoscopy centre of the Norfolk and Norwich University Hospitals NHS Foundation Trust. It is closely allied with the University of East Anglia and the BBSRC. Charles' field of research is infectious diseases and the microbiome and its impact on health and well-being.[1]
Charles was an awarded an OBE in 2023.[2]
Education[edit]
Charles completed a bachelor's degree in Zoology from the University of St Andrews, Scotland, in 1980 and a doctoral degree in Biochemistry from the University of Leicester, UK in 1985.[citation needed]
Career[edit]
Prior to becoming Director of the Quadram Institute, Norwich, UK, Charles was Director of ithree institute in Sydney, Australia, and visiting Professor at University of Technology, Sydney.[3] He has been Professor of Molecular Biology at University of Sheffield and University College London, UK. In 1995 he was a founding member of the Wolfson Institute for BioMedical Research at University College London, one the UK’s first institutes of translational biomedical research.[4]
Charles founded two anti-infectives drug discovery companies. Arrow Therapeutics, sold to AstraZeneca in 2007, and Auspherix founded in 2013. He is currently a Non-Executive Director for Genus plc, and also Co-Founder, Director and Scientific Advisor at Longas Technologies. His earlier commercial career included being Head of Molecular Pharmacology at Glaxo Wellcome; and Senior Research Scientist at Wellcome Research Laboratories.[4]
Selected publications[edit]
Charles' research interests lie in the areas of infectious diseases and the microbiome and their impact on human health.
- Micro-Patterned Surfaces That Exploit Stigmergy to Inhibit Biofilm Expansion (2017)[5]
- A genomic island in Vibrio cholerae with VPI-1 site-specific recombination characteristics contains CRISPR-Cas and type VI secretion modules. (2016)[6]
- Genomic Microbial Epidemiology Is Needed to Comprehend the Global Problem of Antibiotic Resistance and to Improve Pathogen Diagnosis (2016)[7]
- Bacterial Communities Vary between Sinuses in Chronic Rhinosinusitis Patients (2016)[8]
- Coordinating Bacterial Cell Division with Nutrient Availability: a Role for Glycolysis (2014)[9]
- Comparative genomic analysis of a multiple antimicrobial resistant enterotoxigenic E. coli O157 lineage from Australian pigs (2015)[10]
References[edit]
- ^ "Meet the man using 'omics technologies to answer global health questions". Eastern Daily Press. 2020-11-14. Retrieved 2023-10-05.
- ^ "Professor honoured by the King for pioneering research". Eastern Daily Press. 2023-06-17. Retrieved 2023-10-05.
- ^ "Ian Charles to Head the UK's Institute of Food Research". .foodingredientsfirst.com/. Retrieved 2023-10-05.
- ^ a b "Ian Charles". University of East Anglia. Retrieved 4 January 2024.
- ^ Gloag, Erin S.; Elbadawi, Christopher; Zachreson, Cameron J.; Aharonovich, Igor; Toth, Milos; Charles, Ian G.; Turnbull, Lynne; Whitchurch, Cynthia B. (2017). "Micro-Patterned Surfaces That Exploit Stigmergy to Inhibit Biofilm Expansion". Frontiers in Microbiology. 7: 2157. doi:10.3389/fmicb.2016.02157. ISSN 1664-302X. PMC 5253354. PMID 28167929.
- ^ Labbate, M; Orata, FD; Petty, NK; Jayatilleke, ND; King, WL; Kirchberger, PC; Allen, C; Mann, G; Mutreja, A; Thomson, NR; Boucher, Y; Charles, IG (2016). "A genomic island in Vibrio cholerae with VPI-1 site-specific recombination characteristics contains CRISPR-Cas and type VI secretion modules". Scientific Reports. 6: 36891. Bibcode:2016NatSR...636891L. doi:10.1038/srep36891. PMC 5109276. PMID 27845364.
- ^ Wyrsch, Ethan R.; Roy Chowdhury, Piklu; Chapman, Toni A.; Charles, Ian G.; Hammond, Jeffrey M.; Djordjevic, Steven P. (2016). "Genomic Microbial Epidemiology Is Needed to Comprehend the Global Problem of Antibiotic Resistance and to Improve Pathogen Diagnosis". Frontiers in Microbiology. 7: 843. doi:10.3389/fmicb.2016.00843. ISSN 1664-302X. PMC 4908116. PMID 27379026.
- ^ Joss, Tom V.; Burke, Catherine M.; Hudson, Bernard J.; Darling, Aaron E.; Forer, Martin; Alber, Dagmar G.; Charles, Ian G.; Stow, Nicholas W. (2016). "Bacterial Communities Vary between Sinuses in Chronic Rhinosinusitis Patients". Frontiers in Microbiology. 6: 1532. doi:10.3389/fmicb.2015.01532. ISSN 1664-302X. PMC 4722142. PMID 26834708.
- ^ Monahan, Leigh G.; Hajduk, Isabella V.; Blaber, Sinead P.; Charles, Ian G.; Harry, Elizabeth J. (July 2014). "Coordinating Bacterial Cell Division with Nutrient Availability: a Role for Glycolysis". mBio. 5 (3): e00935-14. doi:10.1128/mBio.00935-14. ISSN 2150-7511. PMC 4030479. PMID 24825009.
- ^ Wyrsch, Ethan; Chowdhury, Piklu Roy; Abraham, Sam; Santos, Jerran; Darling, Aaron E.; Charles, Ian G.; Chapman, Toni A.; Djordjevic, Steven P. (March 2015). "Comparative genomic analysis of a multiple antimicrobial resistant enterotoxigenic E. coli O157 lineage from Australian pigs". BMC Genomics. 16 (1): 165. doi:10.1186/s12864-015-1382-y. ISSN 1471-2164. PMC 4384309. PMID 25888127.