Draft:Malini Laloraya

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Dr Malini Laloraya
Born (1964-01-16) 16 January 1964 (age 60)
Allahabad
NationalityIndian
Alma materDevi Ahilya Vishwavidyalaya
Known forResearch on Embryo Implantation, Estrogen Receptor and Polycystic ovary syndrome (PCOS).
Scientific career
FieldsReproduction Biology
InstitutionsRajiv Gandhi Centre for Biotechnology

Malini Laloraya is a Scientist G at Rajiv Gandhi Centre for Biotechnology..[1]She was previously a Senior Lecturer at Devi Ahilya Vishwavidyalaya (Indore). She is an internationally acclaimed scientist who has expertise in Women’s Health issues particularly Implantation Failure and Poly cystic ovary syndrome (PCOS). She was a Raine Visiting Professor awarded by the Raine Medical Research Foundation at the University of Western Australia,[2] Perth, a Rockefeller Fellow at the Population Council (USA) and University of Virginia (USA) and Visiting Faculty Fellow under Healthy Babies program of NIH, University of Florida(USA). She is an Elected Fellow of The National Academy of Sciences (NASI), India, Fellow in Reproduction and Endocrinology(FRE) of SRBCE(India) and an Overseas Fellow of the Royal Society of Medicine[3]

Biography[edit]

She was born on 16th January 1964 in Allahabad. She did her Post Graduation in Devi Ahilya Vishwavidyalaya and PhD in the same university on "Role of free-radicals in luteal steroidogenesis and implantation".

Professional Career[edit]

She worked as Senior Lecturer in Devi Ahilya Vishwavidyalaya after that she is currently working as Scientist G in Rajiv Gandhi Centre for Biotechnology

Professional recognition, awards[edit]

She has achieved significant recognition in the field of reproductive health and fertility. Notable accomplishments include receiving the Prof. P. Govindarajulu Gold Medal Oration in 2020 during the SRBCE Society's annual meeting in Mysuru[4], the Prof. G. P. Talwar Gold Medal Award-2020 at the ISSRF's 30th Annual Meeting, and the Drs. Anant & Lata Labhsetwar Award in 2014 from the Indian Society for the Study of Reproduction & Fertility. Additionally, she served as a Raine Visiting Professor at the University of Western Australia in 2006 and 2008, bestowed by the Raine Medical Research Foundation, Australia. She is also one of the members in 365 Women in STEM [5]

Selected Publication[edit]

1) Krishna MB, Johnson BS, Vasudevan M, Pillai SM, Laloraya M. miRNA-mRNA Network in PBMCs of PCOS Women Identifies Overactivated Stress-Activated Kinases.[6] Cell Physiol Biochem. 2023 Apr 30;57(2):137-156.

2) Renjini Ambika Padmanabhan, Betcy Susan Johnson, Ajay Kumar Dhyani, Sathy M. Pillai, K. Jayakrishnan  and Malini Laloraya.  Autoimmune regulator (AIRE): Takes a hypoxia-inducing factor 1A (HIF1A) route to regulate FOXP3 expression in PCOS.[7] Am J Reprod Immunol. 2023 Feb;89(2):e13637.

3) Padmanabhan RA, Zyju DP, Subramaniam AG, Nautiyal J, Laloraya M. Son of sevenless 1 (SOS1), the RasGEF, interacts with ERα and STAT3 during embryo implantation.[8] J Mol Endocrinol. 2022 Dec 7;70(1):e220089.

4) Betcy Susan Johnson , Meera B Krishna , Renjini A Padmanabhan , Sathy M Pillai , K Jayakrishnan , Malini Laloraya  Derailed peripheral circadian genes in polycystic ovary syndrome patients alters peripheral conversion of androgens synthesis.[9] Hum Reprod. July 30 2022 30;37(8):1835-1855.

5) Joseph A, Nair LCR, Johnson BS, Thomas PL, Padmanabhan RA, Puthumadathil N, Laloraya M.  Transcriptional Regulation of Nos2 via STAT5B Binding to Nos2 Gene Promoter Mediates Nitric Oxide Production: Relevance in β-Cell Maintenance. Cell Physiol Biochem. 2019;52(1):141-155.

  1. ^ "Rajiv Gandhi Centre for Biotechnology". rgcb.res.in. Retrieved 2024-01-24.
  2. ^ archive, From our online (2012-05-15). "Australian honour for RGCB scientist". The New Indian Express. Retrieved 2024-01-24.
  3. ^ "Rajiv Gandhi Centre for Biotechnology". rgcb.res.in. Retrieved 2024-01-24.
  4. ^ "The Secretary presented the minutes of the EC meeting held on 25.11.2021 and the following resolutions of the EC were discussed and approved unanimously" (PDF).
  5. ^ "#365IndianWomenInSTEM Malini Laloraya is a researcher in molecular reproduction whose lab aims to understand events crucial for a successful pregnancy. She pioneered the concept of the positive role of free radicals in reproduction and also studies conditions like PCOS".
  6. ^ Krishna, Meera B.; Johnson, Betcy Susan; Vasudevan, Madavan; Pillai, Sathy M.; Laloraya, Malini (2023-04-30). "miRNA-mRNA Network in PBMCs of PCOS Women Identifies Overactivated Stress-Activated Kinases". Cellular Physiology and Biochemistry: International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 57 (2): 137–156. doi:10.33594/000000622. ISSN 1421-9778. PMID 37125425.
  7. ^ Padmanabhan, Renjini Ambika; Johnson, Betcy Susan; Dhyani, Ajay Kumar; Pillai, Sathy M.; Jayakrishnan, K.; Laloraya, Malini (February 2023). "Autoimmune regulator (AIRE): Takes a hypoxia-inducing factor 1A (HIF1A) route to regulate FOXP3 expression in PCOS". American Journal of Reproductive Immunology (New York, N.Y.: 1989). 89 (2): e13637. doi:10.1111/aji.13637. ISSN 1600-0897. PMID 36305192. S2CID 253184411.
  8. ^ Padmanabhan, Renjini A.; Zyju, Damodaranpillai P.; Subramaniam, Anand G.; Nautiyal, Jaya; Laloraya, Malini (2023-01-01). "Son of sevenless 1 (SOS1), the RasGEF, interacts with ERα and STAT3 during embryo implantation". Journal of Molecular Endocrinology. 70 (1): e220089. doi:10.1530/JME-22-0089. ISSN 1479-6813. PMID 36103132. S2CID 252222084.
  9. ^ Johnson, Betcy Susan; Krishna, Meera B.; Padmanabhan, Renjini A.; Pillai, Sathy M.; Jayakrishnan, K.; Laloraya, Malini (2022-07-30). "Derailed peripheral circadian genes in polycystic ovary syndrome patients alters peripheral conversion of androgens synthesis". Human Reproduction (Oxford, England). 37 (8): 1835–1855. doi:10.1093/humrep/deac139. ISSN 1460-2350. PMID 35728080.