Hervotype

Hervotype^[1] is a specific sequence of a particular human endogenous retroviral (HERV) insertion. Hervotyping, like genotyping, is the process of determining the specific sequence of a particular HERV. With more research on HERV, it is now known that HERV may not be monomorphic and a HERV insertion may be present in various alleles. Therefore, it is important to know the hervotype of a HERV insertion as the sequences can give more information on their ages. It is now believed that it is not enough to say whether a HERV is present or present in full form but hervotypes are essential in evaluating their relationship to human disease and to know their true contribution in evolution of humans.

References[edit]

^ Jha, A. R.; Pillai, S. K.; York, V. A.; Sharp, E. R.; Storm, E. C.; Wachter, D. J.; Martin, J. N.; Deeks, S. G.; Rosenberg, M. G.; Nixon, D. F.; Garrison, K. E. (2009). "Cross-Sectional Dating of Novel Haplotypes of HERV-K 113 and HERV-K 115 Indicate These Proviruses Originated in Africa before Homo sapiens". Molecular Biology and Evolution. 26 (11): 2617–26. doi:10.1093/molbev/msp180. PMC 2760466. PMID 19666991.

[1] Jha, A. R.; Pillai, S. K.; York, V. A.; Sharp, E. R.; Storm, E. C.; Wachter, D. J.; Martin, J. N.; Deeks, S. G.; Rosenberg, M. G.; Nixon, D. F.; Garrison, K. E. (2009). "Cross-Sectional Dating of Novel Haplotypes of HERV-K 113 and HERV-K 115 Indicate These Proviruses Originated in Africa before Homo sapiens". Molecular Biology and Evolution. 26 (11): 2617–26. doi:10.1093/molbev/msp180. PMC 2760466. PMID 19666991.

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