Lederbergvirus
| Lederbergvirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Duplodnaviria |
| Kingdom: | Heunggongvirae |
| Phylum: | Uroviricota |
| Class: | Caudoviricetes |
| Order: | Caudovirales |
| Family: | Podoviridae |
| Genus: | Lederbergvirus |
Lederbergvirus (synonyms P22-like viruses, P22-like phages, P22likevirus) is a genus of viruses in the order Caudovirales, in the family Podoviridae. Bacteria serve as natural hosts, with transmission achieved through passive diffusion. There are six species in this genus.[1][2][3]
Taxonomy[edit]
The following six species are assigned to the genus:[2]
- Escherichia virus HK620
- Salmonella virus BTP1
- Salmonella virus P22
- Salmonella virus SE1Spa
- Salmonella virus ST64T
- Shigella virus Sf6
Structure[edit]
Lederbergviruses are nonenveloped, with a head and tail. The head is icosahedral with T=7 symmetry, with a diameter of approximately 60 to 65 nm. The tail is non-contractile with six prominent tail spikes.[1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Lederbergvirus | Head-Tail | T=7 | Non-enveloped | Linear | Monopartite |
Genome[edit]
Several species have been fully sequenced. They range between 38k and 42k nucleotides, with 58 to 72 proteins. Complete genomes, as well as several similar unclassified strains are available from [1][3]
Life cycle[edit]
Viral replication is cytoplasmic. The virus attaches to the host cell using its terminal fibers, and ejects the viral DNA into the host periplasm. DNA-templated transcription is the method of transcription. Once the viral genes have been replicated, new virions are assembled in the host's cytoplasm, and mature virions are released via lysis and holin/endolysin/spanin proteins.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Lederbergvirus | Bacteria | None | Injection | Lysis | Cytoplasm | Cytoplasm | Passive diffusion |
History[edit]
According to ICTV's 1996 report, the genus P22likevirus was first accepted under the name P22-like phages, assigned only to family Podoviridae. The whole family was moved to the newly created order Caudovirales in 1998, and the genus was renamed to P22-like viruses in ICTV's seventh report in 1999. In 2012, the genus was renamed again, this time to P22likevirus.[2] The genus was later renamed to Lederbergvirus.
References[edit]
- ^ a b c "Viral Zone". ExPASy. Retrieved 1 July 2015.
- ^ a b c "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 12 May 2021.
- ^ a b NCBI. "P22likevirus Complete Genomes". Retrieved 18 February 2015.
External links[edit]