Pipethiaden

Pipethiaden
Clinical data
ATC code	None;
Identifiers
	IUPAC name 1-Methyl-4-(thieno[2,3-c][2]benzothiepin-4(9H)-ylidene)piperidine;
CAS Number	15053-99-3;
PubChem CID	197209;
ChemSpider	170786;
UNII	4M164I6E36;
CompTox Dashboard (EPA)	DTXSID70164567 ;
Chemical and physical data
Formula	C18H19NS2
Molar mass	313.48 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC(=C2c3ccccc3CSc4c2ccs4)CC1;
	InChI InChI=InChI=1S/C18H19NS2/c1-19-9-6-13(7-10-19)17-15-5-3-2-4-14(15)12-21-18-16(17)8-11-20-18/h2-5,8,11H,6-7,9-10,12H2,1H3; Key:VZWWTHTUQTYAGH-UHFFFAOYSA-N;

Pipethiaden is a benzothiepin-based drug candidate that was at one time studied as a potential preventive to reduce the frequency of recurrent migraine headaches. It also has some activity as an antihistamine acting mainly at the 5-HT_2A and 5HT_2C receptors.^[2]

References[edit]

^ "1-Methyl-4-(thieno[2,3-c][2]benzothiepin-4(9H)-ylidene)piperidine".
^ Frycová H, Metys J (July 1989). "[Anti-allergic properties of pipethiaden--a new preventive agent for migraine]". Ceskoslovenska Farmacie (in Czech). 38 (6): 264–8. PMID 2790993.

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[1] "1-Methyl-4-(thieno[2,3-c][2]benzothiepin-4(9H)-ylidene)piperidine".

[2] Frycová H, Metys J (July 1989). "[Anti-allergic properties of pipethiaden--a new preventive agent for migraine]". Ceskoslovenska Farmacie (in Czech). 38 (6): 264–8. PMID 2790993.

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