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Miguel Cotto vs. Antonio Margarito, billed as "The Battle", was a professional boxing match between WBA welterweight champion Miguel Cotto and former IBF and WBO welterweight champion Antonio Margarito. The WBA welterweight title bout took place on July 26, 2008, at the MGM Grand in Paradise, Nevada, and resulted in an eleventh round technical knockout victory for Margarito.

Both men had previously fought on April 12 and emerged victorious, thus clearing the way for a July 26 match between the two boxers. It was Cotto's first fight in Las Vegas since December 2004. According to promoter Bob Arum, the bout took place in Las Vegas to promote Cotto to a new audience while also appealing to Margarito's Mexican American fans in California. Cotto entered the fight as The Ring magazine's #1 ranked boxer in the welterweight division and #6 in their pound-for-pound rankings. Margarito entered the match as The Ring magazine's #4 ranked welterweight. Press conferences were held in Mexico, Los Angeles, New York City, and Puerto Rico to promote the world title bout.

Cotto and Margarito's aggressive boxing styles led to much praise from multiple boxing writers. Kevin Iole of Yahoo! Sports named it the third-best boxing match of 2008 and the fight generated 450,000 pay-per-view buys, the third-highest in 2008 for a boxing match. Margarito was later suspected of cheating in this bout after controversy arose over his use of hand wraps after his bout with Shane Mosley.