Roger Foo

Roger Foo
Scientific career
Fields	Cardiology
Institutions	Yong Loo Lin School of Medicine

Roger Foo is a cardiologist. He is the inaugural chair holder of the Zayed bin Sultan Al Nahyan Professorship of Medicine at the National University of Singapore (NUS) Yong Loo Lin School of Medicine, where he is also Vice Dean (Research) and Head of the Clinician Scientist Academy. He is the Director of the Cardiovascular Disease Translational Research Programme, Director of the Cardiovascular Research Institute (CVRI), Senior Consultant in the National University Heart Centre, and also Adjunct Prinicipal Investigator at the A*STAR Institute of Molecular and Cell Biology (IMCB).

Research work

Foo's lab was the first to publish an epigenomic map of the failing human heart in 2011. More recently, his lab has published an in-depth analysis of the cardiac chromatin 3D organisation and delineated detailed maps of cardiac enhancer-promoter interactions, enhancer genetics, and also through cardiomyocyte single nuclear sequencing reported the discovery of a long noncoding RNA, called Singheart, which regulates key cardiac gene expression. The approach of the lab is to deep dive into the epigenome of the heart, using advanced technology including Crispr-genome editing to explore frontiers, in continuing aspirations to discover novel avenues for therapies or biomarkers. Foo has also published on the application of Next Generation Sequencing genomics to patients in the clinic, and most recently was involved in the first phase of the innovative SG10K genomics project in Singapore.