Talk:Betamethasone

Untitled

Just taking an ad out - scrubbing the name Schering-Plough like it's on a billboard--Menswear 21:05, 16 December 2006

Blood glucose lvls

In this article it states that this medication causes hypoglycemia, yet, as its typical with corticosteroids, it actually causes an increase in blood sugars —Preceding unsigned comment added by 134.29.231.70 (talk) 14:34, 15 October 2007 (UTC)

The article is correct, in that it says it may cause hypoglycemia in the NEWBORN, not the foetus. You are right that steroids will cause an increase in sugar, primarily in the mother, which will be carried via the placenta to the foetus. The foetal pancreas will respond by releasing insulin, but that insulin will be insufficient to overcome the high volume of sugars released from maternal stores until the baby is liberated from the continuing influx of sugar through delivery, at which point the newborn child's high insulin output will cause the sugars to drop, sometimes exceedingly low.

In an ideal situation, the betamethasone is administered to the mother far enough in advance of delivery that her serum glucose levels will somewhat normalise, as will foetal insulin levels (and, of course, far enough in advance to allow for proper lung maturation to take place). DoctorEric (talk) 17:22, 12 July 2011 (UTC)

WikiProject class rating

This article was automatically assessed because at least one WikiProject had rated the article as stub, and the rating on other projects was brought up to Stub class. BetacommandBot 07:51, 10 November 2007 (UTC)

IUPAC name is incorrect

There is no H in 9, 10, 13, 17 positions. —Preceding unsigned comment added by 141.211.71.87 (talk) 16:38, 20 April 2010 (UTC)

I think the "hydro" part of the name means that there is no double bond (modification of the "phenanthren" parent structure), and then the structure is modified further by, for example, replacing H9 with F (the usual meaning of "fluoro"). Without the "hydro" part, position 9 would exceed its octet. Working from the parent structure back towards the beginning of the name, each modifies the previous result. There are other systematic approaches that are not as confusing sometimes. For example, "(11β,16β)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-​diene-3,20-dione" (systematic name according to ChemSpider) uses a parent structure that does not have to be modified two ways at the same place. DMacks (talk) 16:56, 20 April 2010 (UTC)

Celestamine

I've made brief mention of Celestamine, a brand name for Betamethasone produced by Schering-Plough. But are they exactly the same, or does Celestamine have additional ingredients? I'm not sure. — Preceding unsigned comment added by Onanoff (talk • contribs) 13:50, 30 January 2011 (UTC)

• I removed the addition due to the promotional nature. Additionally, the links provided are unreliable and inappropriate to support content on Wikipedia. Cind.amuse 14:12, 30 January 2011 (UTC)

References

Phimosis and References

While I agree with the inclusion of the paragraph about using betamethasone cream as a 1st-line treatment of paediatric phimosis, it seems odd that 5 of the 6 referenced sources for the article are devoted to supporting that 2-sentence paragraph, while most of the article's information remains unreferenced. I'd suggest paring down the circ refs to the 2-3 best ones, and adding new references to support other parts of the artilce. DoctorEric (talk) 17:29, 12 July 2011 (UTC)

To reduce inflammation in spinal disc conditions?

I was just injected with 12 mg of this medication for such a condition. I find it interesting that no mention is made of this usage, since corticosteroid injections seem to be a major tool in combating back pain/injury. Huw Powell (talk) 05:47, 29 June 2016 (UTC)

Coincidentally, I was just injected with this medication for the same condition. During my research, it seems this use of this drug is currently not approved by the FDA despite it having been used for this condition for decades. That is probably why it is not included in the text of the article. WarFighter (talk) 18:13, 1 May 2019 (UTC)

External links modified

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