Talk:Biguanide

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Untitled[edit]

Biguanides are not only antidiabetic medications. They also include proguanil (antimalarial), chlorhexidine gluconate (antimicrobial/antiviral), 2-guanidinebenzimidazole (decreases gastic acid secretions). How can we modify the article to include the broad spectrum of the biguanide and its derivatives? rmosler 08:13, 26 October 2006 (UTC)[reply]

Agree. According to this source, Chlorhexidine is "hexamethyl bischlorophenyl biguanide". Should it be categorised as a biguanide and mentioned here? This is a major antiseptic. Colin°Talk 20:07, 21 December 2009 (UTC)[reply]

Structure and name[edit]

It looks like a bi-Guanidine. Can we say if this is the origin of the name ? - Rod57 (talk) 12:57, 29 June 2016 (UTC)[reply]

kan het nederlands worden vertaald[edit]

het is zo vervelend dar het op mijn computer engels is kan je dat veranderen 2A02:A45B:4D45:1:CDB3:1334:D64:DE93 (talk) 13:00, 9 October 2022 (UTC)[reply]

The image of the ball and stick model appears to be incorrect[edit]

..or at least it doesn't agree with the other image of the structure and the formula, the latter given as HN(C(NH)NH_2)_2 . The ball-and stick model has formula (NH_2)_2CNC(NH)NH_2 In fact, they are isomers. 147.147.218.218 (talk) 02:02, 31 December 2023 (UTC)[reply]

They are tautomers. See https://doi.org/10.1016/j.molstruc.2017.08.100 for the full story. The skeletal formula should probably be changed to match the ball-and-stick model, and the tautomerism should be explained in the article body. Ben (talk) 02:58, 31 December 2023 (UTC)[reply]