Talk:Desmoteplase

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Draculin[edit]

What's the difference to Draculin? Is it the same?--Kuebi —Preceding comment was added at 10:51, 8 November 2007 (UTC)[reply]

The answer is given below. Chhandama (talk) 12:48, 6 June 2017 (UTC)[reply]

Merger proposal[edit]

The result of this discussion is no consensus. North America¹⁰⁰⁰ 09:51, 6 August 2017 (UTC)[reply]

The following discussion is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

This page was proposed for merger with draculin by Totodu74 on 10 January 2016 (wihout opening a discussion or making any query).

The pages should not be merged because desmoteplase and draculin are different proteins, albeit both from the saliva of bat, as made clear in the article by Low et al. (see doi:10.1016/j.jprot.2013.05.034). In brief,

Desmoteplase, discovered in 1932, is a fibrinolytic enzyme and plasminogen activator, actually exists is four types, smaller in size, and is used in clinical trial as a drug for acute ischemic stroke.
Draculin, discovered in 1995, is a plasminogen inhibitor lacking fibrinolytic activity, and a much larger 88.5 KDa protein with no known—so far—medical use.

Hence, separate articles are warranted. Chhandama (talk) 12:48, 6 June 2017 (UTC)[reply]

The discussion above is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.