Talk:Glucagon

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Wiki Education Foundation-supported course assignment[edit]

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Rafaelvazquez.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 22:28, 16 January 2022 (UTC)[reply]

Glucagon and Glucose[edit]

Extract from the article - "Glucagon also regulates the rate of glucose production through lipolysis." Are we sure about this statement? I thought lipolysis is the breakdown of fat stored in fat cells, releasing free fatty acids. —Preceding unsigned comment added by 78.99.44.255 (talk) 23:10, 12 August 2008 (UTC)[reply]

In addition, glycerol is released which is then converted to glucose in the liver. TheTrojanHought (talk) 19:14, 13 April 2009 (UTC)[reply]

There is some controversy. At least two studies point out that glucagon has no impact on lipolysis: http://www.ncbi.nlm.nih.gov/pubmed/11238513 and http://www.ncbi.nlm.nih.gov/pubmed/11344211. Is there a citation supporting that statement? — Preceding unsigned comment added by RicarDog (talkcontribs) 07:27, 8 May 2012 (UTC)[reply]

Transdermal Glucagon Patch[edit]

Just wondering, is there any prospect for a transdermal glucagon patch in the future? —Preceding unsigned comment added by Interestedperson (talkcontribs) 21:00, 26 September 2007 (UTC)[reply]

WikiProject class rating[edit]

This article was automatically assessed because at least one WikiProject had rated the article as start, and the rating on other projects was brought up to start class. BetacommandBot 16:27, 10 November 2007 (UTC)[reply]

Page Layout Error?[edit]

There appears to be an error with this page. Some overlapping text appears in the "Uses" section. It might be my browser(firefox), but I doubt it. It would be great if someone else fixed this because I'm not sure how to do it. --Jmz9466 (talk) 21:13, 11 May 2008 (UTC)[reply]

Image not proper!![edit]

I've noticed that the image for glucagon has been replaced by an ad. I tried to repair it by undoing one of the edits, but it didn't work. Please fix it. And to the one who caused this vandalism: you should be ashamed for destroying wikipedia!! —Preceding unsigned comment added by Deltawarrior60 (talkcontribs) 23:23, 19 July 2008 (UTC)[reply]

Seems to have been fixed. JFW | T@lk 14:02, 20 July 2008 (UTC)[reply]

The structure of glucagon is NOT glucagon! PDB 1D0R corresponds to glucagon-like peptide 1 (GLP-1) which is NOT glucagon. These are different molecules, with different biological functions. The title of the PDB entry: SOLUTION STRUCTURE OF GLUCAGON-LIKE PEPTIDE-1-(7-36)-AMIDE IN TRIFLUOROETHANOL/WATER . — Preceding unsigned comment added by Truthortruth (talkcontribs) 16:26, 20 September 2011 (UTC)[reply]

Glucagon Other Uses[edit]

I believe there should be some mention of glucagon as a smooth muscle relaxant and its use in oesophageal and airway obstruction.

Dfor50 (talk) 01:12, 27 September 2009 (UTC)[reply]


I also think it is worth having the article mention that Glucagon can be a very effective antagonist of calcium channel blockers. Not only can this bit of info be life saving in the event of a CCB overdose but is important information when considering Glucagon's use by those who also are being treated for high blood pressure. I don't have access to the journals to dig up proper peer reviewed references. I could find some online references such as: [1] [2] JJ Bosch (talk) 04:42, 29 October 2009 (UTC)[reply]

References

  1. ^ Glucagon antagonism of calcium channel blocker-induced myocardial dysfunction. Crit Care Med. 1988; 16(3):246-51 (ISSN: 0090-3493) at medscape.com
  2. ^ Dave Ross's column at www.jems.com titled "Calcium Channel Blocker Overdose" - http://www.jems.com/news_and_articles/columns/Ross/Calcium_Channel_Blocker_Overdose.html

"Eyestalk removal?"[edit]

...what in the hell is *that* supposed to prove that another test couldn't have? No, seriously, where's PETA when you need them? Granted, crayfish are invertebrates, but someone should have stopped whoever did that study. It comes across as "I was desperate for a dissertation" based sadism. ...Just sayin'. ...I'm not really sure what it is supposed to contribute to the discussion of glucagon here. On top of everything else, it comes across as trivia. 65.27.134.29 (talk) 02:24, 11 March 2012 (UTC)Ubiquitousnewt[reply]

...In fact, I'm taking it out on the grounds of "it's irrelevant." If someone else wants to edit it back, be my guest. 65.27.134.29 (talk) 02:26, 11 March 2012 (UTC)Ubiquitousnewt[reply]

Glucagon vs. Glucagen[edit]

It would be nice to mention Glucagen here. Glucagen is (supposedly) the same as glucagon, except that it is made rDNA (recombinant DNA, i.e. GMO) using bacteria instead of extracted from animal organs.

Likewise, I'd like to see other trade names for Glucagon listed.

Separate topic: Dfor50 suggests "there should be some mention of glucagon as a smooth muscle relaxant and its use in oesophageal and airway obstruction." It is often used alone or in combination with EZ gas to free stuck food in the esophagus. — Preceding unsigned comment added by Radiodave2 (talkcontribs) 16:38, 19 August 2012 (UTC)[reply]

Review[edit]

An anonymous editor dropped doi:10.1677/JOE-08-0290 in the "external links" section. It is a good secondary source so I thought I'd at least put it here. JFW | T@lk 21:50, 19 April 2014 (UTC)[reply]