Talk:Kinesin

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Wiki Education Foundation-supported course assignment[edit]

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Jenn545. Peer reviewers: Jenn545.

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Wiki Education Foundation-supported course assignment[edit]

This article was the subject of a Wiki Education Foundation-supported course assignment, between 7 January 2019 and 30 April 2019. Further details are available on the course page. Student editor(s): Kaden.Rawson.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 23:41, 17 January 2022 (UTC)[reply]

Wiki Education Foundation-supported course assignment[edit]

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Aishashok06, Randallr94, ScienceFaction.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 01:47, 17 January 2022 (UTC)[reply]

Molecular motors UofU Spring 2019 class project[edit]

Several of my classmates and I have been tasked with editing and making additions to the Kinesin page. Our intent is to add a subsection about kinesin regulation, including autoinhibition and phosphorylation. We will also attempt to clarify some of the diagrams by providing pictures of kinesin mounted to a microtubule. Feel free to reach out to us for guidance and support. We look forward to working with you. Kaden.Rawson (talk) 18:47, 2 April 2019 (UTC)[reply]

Tagged as confusing[edit]

I noticed this article was tagged as confusing, so I'm creating a talk page for people to hash it out. I think there might be a mistake on the page with respect to "polarity" and kinesin. What I think the author of that section is trying to say is that the kinesin protein itself tends to "walk" to the + end of the microtubule, and not that kinesin itself has a + end. Could someone please clarify? 64.59.144.85 06:21, 23 January 2007 (UTC)[reply]

As far as I know, kinesins do not have a + end per se (ignoring any charge residues). The section on polarity is most likely referring to the microtubule, which does have a + and a - end assigned to it. I'm going to change it, but it would be great if someone could double-check for me - this isn't quite my field. Jenalala 06:28, 23 January 2007 (UTC)[reply]
You are correct. As far as I've been able to determine from the literature, kinesins and dyneins do not have a polar end and the author was referring to directionality of their "hand-over-hand" movement down microtubules. Some of the most recent literature suggests the dynein-dynactin motor complex is actually quite flexible in directionality, which makes sense when considering intracellular transport. If a microtubule pathway was blocked, nothing would stop an endless trainwreck of unidirectional motor proteins carrying loads of mitochondria, actin filaments, vesicles, and smooth ER (in the case of axons). — Preceding unsigned comment added by 163.118.222.122 (talk) 15:56, 26 February 2007‎ (UTC)[reply]
I'm familiar with kinesin and have updated the page. --Richwil 13:32, 30 March 2007 (UTC)[reply]
From my understanding, kinesins (at least Kinesin-1) move toward the + end of the microtubule, in the anterograde direction. I will double check and correct if necessary. Mikmd —Preceding signed but undated comment was added at 14:12, 19 September 2007 (UTC)[reply]

Lead section[edit]

When I visited the page Oct 2007, the article was lacking a lead section, i.e. a commonly understood short section (max. 4 paragraphs) explaining the essentials. I attempted to write that and keep out too much jargon or explaining it in brackets. Feel free to improve it. Jakob Suckale 16:36, 11 October 2007 (UTC)[reply]

Teletubby goin' round[edit]

Animation of kinesin walking on a microtubule

I think this crazy anim isnt on topic. its disturbing like an ad. one cannot concentrate on contents. so i discarded it. --77.182.172.61 (talk) 09:02, 24 May 2013 (UTC)[reply]

It was added back a month later. --83.255.52.110 (talk) 16:39, 23 April 2014 (UTC)[reply]

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Section 'Mechanism of movement' is confusing - talks of "heads"[edit]

That threw me. Calling them feet makes the analogue more familiar. 78.146.83.112 (talk) 13:25, 6 February 2024 (UTC)[reply]

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