Talk:Lipofuscin

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History[edit]

Who discovered lipofuscin? — Preceding unsigned comment added by 83.53.84.4 (talk) 17:13, 18 April 2017 (UTC)[reply]

Olfactory epithelium[edit]

Ross & Pawlina: Histology text & atlas, 5ed pp. 615-6 specifically mentions that supporting (sustentacular) cells in olfactory epithelium contain lipofuscin (like I guess pretty much all cells), and that this is making olfactory epithelium "slight yellowish brown". Does this color accumulate after birth or is it constant? Are there any known functions for this lipofuscin there? VilleSalmensuu (talk) 07:49, 20 January 2008 (UTC)[reply]

REDIRECT Target page name

Products[edit]

2019 Vita Technologies, Inc. http://www.vitatech4life.com, http://www.rewirewater.com

I am interested in finding links to sites that have products that can remove this from the body. Researchist 21:35, 4 February 2007 (UTC)[reply]

Ha ha. So is everyone. There do not yet appear to be any such compounds or substances. linas 03:12, 16 July 2007 (UTC)[reply]

Yup, my guess is there are people still experimenting with this. Look into people analyzing soils samples for different bacterial cultures, they're experimenting with introducing these into cells to see if they'll eat them. If they can break down lipofuscin in a graveyard, maybe they could in a living human with some pharmaceutical assistance. The main thing is testing for side effects and how to safely introduce to the most heavily affected (or least risky) cells. Tyciol (talk) 01:20, 11 December 2008 (UTC)[reply]

Recent research suggests that a small molecule drug (beta cyclodextrins) may be able to remove lipofuscin bisretinoids and could be a treatment or prophylactic for Stargardts^[1] Jimbrizzy (talk) 00:13, 16 July 2014 (UTC)[reply]

The link to this reference seems to be dead: Chris Gaugler, "Lipofuscin", Stanislaus Journal of Biochemical Reviews May 1997 Google searches with words from this, however, quickly lead to sites selling vitamin supplements purporting to turn back the dreaded clock, leading me, at least, to feel a little suspicious of this whole article ... — Preceding unsigned comment added by 115.64.142.162 (talk) 07:28, 12 May 2017 (UTC)[reply]

... the links worked for me:

1997 Chris Gaugler and Koni Stone https://web.archive.org/web/20070715160509/http://wwwchem.csustan.edu/chem4400/SJBR/lipofus.htm

. includes refs: https://web.archive.org/web/20070715160550/http://wwwchem.csustan.edu/chem4400/SJBR/chrisGlit.html Wikipaddn (talk) 19:02, 11 December 2017 (UTC)[reply]

References

^ http://www.pnas.org/content/111/14/E1402

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Misplaced paragraph?[edit]

Does the paragraph beginning, "The ABCR -/- knockout mouse has delayed dark adaptation but normal final rod threshold relative to controls." belong in the next section? It's about macular degeneration, which is the topic of that section. IAmNitpicking (talk) 13:57, 9 July 2019 (UTC)[reply]

External links[edit]

I think at least two of the external links here are inappropriate and possible spam. I am asking for consensus rather than starting an edit war. IAmNitpicking (talk) 12:33, 13 May 2023 (UTC)[reply]

[1] ttp://www.pnas.org/content/111/14/E1402

[1]