Talk:Methacholine

Pharmacology Mid‑importance

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Medicine Mid‑importance

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Methacholine.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Susceptibility to Acetylcholinesterase[edit]

Quote from the article: "It is broken down at a relatively slow rate within the body, due to its resistance to acetylcholinesterases. Methacholine has a β-methyl group which provides selectivity towards M-type receptors as compared to N-type receptors. The quarternary ammonium group is essential for activity. The ester however makes it susceptible to the enzyme acetylcholine esterase.[2]" These statements are seemingly contradictory. Is it susceptible to AchE? If so, to what degree? Dryphi (talk) 03:35, 2 June 2011 (UTC)[reply]

Dead link[edit]

Reference 2 doesn't link to anything, or exist. 129.78.56.166 (talk) 11:32, 31 August 2018 (UTC)[reply]

I fixed the link. Thanks for catching the problem and reporting it here. -- Ed (Edgar181) 12:15, 31 August 2018 (UTC)[reply]