Talk:Phenazepam

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I've put a pharma-stub tag on this. The article is rather short. I guess that this is a fairly recent drug, as I've never heard of it before. I couldn't find it when I searched British National Formulary.

From web searches, it seems that this drug is more popular in the East - many of the pages I come up with are in Russian or other non-latin-alphabet languages. Also, I draw a blank when trying my favourite English-language sources.

--Publunch 18:02, 1 December 2006 (UTC)[reply]

Hi there! Phenazepam was introduced in the mid 80`s in Soviet Union and became very popular for treatment of different neurological diseases. It`s chemical structure closely resembles bromazepam, except that pyridine ring is replaced by o-chlorophenyl one.

You are quite right, it is chemically very close to bromazepam, though subjectively, mg for mg, it is a lot stronger. It has been around for well over 20 years now, and is quite popular as an anxiolytic in the former Eastern Bloc. It produces less of a euphoriant effect than bromazepam, though more in the way of sedation. As for Legal Status, neither the UK nor US Laws on controlled substances mention Phenazepam. Therefore we would be probably correct if we were to assert that this substance is not illegal in any way in the UK or US. I am not surprised that it can not be found in the British National Formulary - of the nearly 40 benzodiazepines, only ten are included in that publication. The rest have been deleted over the past fifteen years or so, bromazepam being the latest in 2003. British doctors have the least amount of benzodiazepines that they are able to prescribe of all Western countries, which is why diazepam, considered old-fashioned and not used much any more in the rest of the world, is the #1 choice benzo for UK doctors. Even alprazolam is being phased out. Gauchoamigo —Preceding unsigned comment added by Gauchoamigo (talk • contribs) 00:59, 6 November 2007 (UTC)[reply]

Actually it is much closer to clonazepam, differing only by one group at the 7-position. On clonazepam it is a nitro group (NO2) on phenazepam the nitro group has been replaced by a bromo group

-7-bromo- 5-(2-chlorophenyl)- 1,3-dihydro- 2H- 1,4-benzodiazepin- 2-one

-7-nitro-5-(2-chlorphenyl)-2,3-dihydro-1,4-benzodiazepin-2-on

--Rollie (talk) 21:32, 28 July 2010 (UTC)[reply]

I edited the IUPAC Name since the old one was not appropriate--ChemSpiderMan (talk) 01:56, 20 December 2007 (UTC)[reply]

Flunitrazepam (Rohypnol(r)) is schedule I in the US. Couldn't this drug therefore be schedule I under the analog act? —Preceding unsigned comment added by 67.85.180.97 (talk) 00:16, 3 March 2009 (UTC)[reply]

That is false. Flunitrazepam is Schedule IV under US Federal law. Only in a few states is it Schedule I. In those few states, if those states had an analog act, then phenazepam could be considered an analog in those states only. Under Federal law, however, flunitrazepam is clearly in Schedule IV, therefore, phenazepam cannot be an analog under Federal law. 71.178.48.73 (talk) 02:01, 22 March 2010 (UTC)[reply]

Any ideas about it's legality n other countries? —Preceding unsigned comment added by 114.77.206.213 (talk) 07:12, 2 November 2009 (UTC) It's totally legal in the UK, and unless your country has an analogue act that applies to 1,4-benzodiazepines, or it's mentioned by name or chemical formula in your countries "misuse of drugs act" (or whatever they call it in your home country) then it's legal. It would probably be restricted in the old USSR satellite countries, since it was developed and still is used there. Most of Europe, except Norway is fine I think --Rollie (talk) 21:32, 28 July 2010 (UTC)[reply]

Let me just say that this phenazepam stuff should definitely be a controlled substance. It nearly cost me my life. —Preceding unsigned comment added by 68.103.93.181 (talk) 06:58, 11 February 2010 (UTC)[reply]

No, YOU, almost cost YOU your life. Go ahead, get the goverment to wipe your ass for you and dole out your tylenol one at a time at the expense of every intelligent persons freedom and quality of life. People like you are disgusting. Thank God I can get a beer after work, even though some people like to drink a whole bottle of Vodka, and blame the government for not protecting them from it. You, are an IDIOT.

I agree. It nearly cost you your life because you lack self control and safety. it is YOUR problem if you screw up, no one else's. —Preceding unsigned comment added by 132.198.39.35 (talk) 20:32, 18 April 2010 (UTC)[reply]

Perhaps people should do a little more reading before opening their mouths.

Like other Benzodiazepines, the addiction potential of phenazepam is very high. Neurochemical changes from the chronic use of Benzodiazepines was noted as early as 1981.[Medical Research Council Benzodiazepine Dependence][83] These alterations created a physical dependence on the drug which may become dangerous if use is stopped abruptly.

Withdrawal symptoms range from restlessness, anxiety, and insomnia to convulsions or seizures. Rarely, death may occur during inadequately treated withdrawal from benzodiazepines.[61] Withdrawal symptoms worse than mild anxiety should be treated with the assistance of a physician. A tapered dose of a benzodiazepine may be prescribed. Admission to hospital is necessary for severe symptoms. (drugs-forum.com)

Now imagine someone taking Phenazepam recreationally and with responsibility, say 1mg a day, the half life of that stuff is over 60 hours long.(has it been proven in a study that the halflife is 60 hours long, people on the net have experimented and say its over rated and very mild substance at best)(only good for alchol and drug withdrawls)probably in the bottom 5 weakest benzodiazapines out there) Hence it stays in your system and builds up. Causing an addiction. Thats where black outs and amnesia set in not to mention the depression and suicidal thoughts. Seriously kids.... Read and Be Safe! —Preceding unsigned comment added by Singlecelled0rgan1zm (talk • contribs) 02:06, 5 November 2010 (UTC)[reply]

Phenazepam is probably the best pills to cure anxiety QUICKLY (during 15-30 min) and obsessive-compulsive disorder.

Half of 0,001 or 0,0005 pill and you don't fill anxiety at all. Method of cure: 1/2 of pill every 4 hours and before sleep - reducing doze after 7-10 days to 1/4 of pills depending on your condition and then slowly to stop taking it. Combining Phenazepam with French-made Eglonil (Sulpiride): 1/2 0,001 Phenazepam + 1/2 Eglonil will rapidly increase effect and effectively increase good mood, motivation and performance.(Works after 30- 40 min for 4 hours) Phenazepam was discovered and developed in 60s by Soviet Scientists which were awarded for development of Phenazepam by Order of Lenin- higher order in USSR. Note that. p.s. don't over-doze. Taking pills as described above will quickly cure and keep you motivated adequate person. If you need more quick effect (in 5-10 min)- chew tablet. After course of cure- take phenazepam "by health". Note: this is medical drug. Not candy or pills of happiness. Hope this will help. — Preceding unsigned comment added by 213.227.230.68 (talk) 22:00, 8 July 2011 (UTC)[reply]

Phenazepam is a real threat for the Western farma corporations and their profits. It is much more effective AND HAVING SIGNIFICANTLY LESS SIDE EFFECTS than Diazepam (partially because only 0.5mg replace 10mg of Diazepam). And it is cheap. This is why those transnational corporations go to the far ends trying to prohibit it in US, UK etc. Open your eyes. Recreational use? That's because it's cheap and unsupported by the mainstream healthcare system in Western countries. But it was designed for use as medication, not for recreational use. — Preceding unsigned comment added by 89.255.92.12 (talk) 00:21, 23 November 2012 (UTC)[reply]

Corrections[edit]

Molecular formula: C₁₅H₁₀ON₂BrCl → Molecular weight = 349.61 g·mol^-1. --Cjp24 (talk) 12:49, 7 July 2015 (UTC)[reply]

Misuse of Drugs Act[edit]

Could anyone explain why there's no mention of phenazepam in the text of Misuse of Drugs Act? --81.147.136.84 (talk) 07:40, 4 August 2016 (UTC)[reply]

For unknown reasons they prefer to list a million amendments instead of updating the main law on their website. You can check out the phenazepam ruling here and the explanation here. Aethyta (talk) 17:29, 4 August 2016 (UTC)[reply]