Talk:Tetrahydrocannabinol/Archives/2023

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Confusing sentence

I find this sentence in the intro confusing: "Like most pharmacologically active secondary metabolites of plants, THC is a lipid found in cannabis, assumed to be involved in the plant's evolutionary adaptation, putatively against insect predation, ultraviolet light, and environmental stress."

Is it trying to say that most pharmacologically active metabolites in plants are lipids? Was it rewritten at some point and the "like most pharmacologically active secondary metabolites of plants..." part originally referred to "assumed to be involved in the plant's evolutionary adaptation...?"

As written, it sounds like it's saying most pharmacologically active metabolites of plants are lipids which are found in cannabis, but that's obviously not true or the intended meaning. Formallydehyde (talk) 01:18, 1 September 2022 (UTC)

Fixed, thank you Gbezpz (talk) 17:27, 30 October 2022 (UTC)

Lethal dose

I have changed ==No known lethal dose== to ==Unknown lethal dose== because it is less susceptible to misunderstanding. The old section heading could be misunderstood as meaning that there is a thing called a 'known lethal dose', and it has been proven not to exist – always perfectly safe, even if you drink gallons of pure THC. The new wording is clearer that this level is unknown.

IMO it would be ideal for this section to explain what a lethal dose means. You can drown in a cup of water, but that's not the same as dying from toxicological effects of water. A large adult would need to drink about 9 liters of water to die from its toxicological effects. The same large adult, if too injured to move to safety, can die by falling face-first in a shallow rain puddle. Similarly, people die from consuming cannabis, even if it's not through the exact method measured by the LD50. WhatamIdoing (talk) 18:00, 28 October 2022 (UTC)