Template:2021–22 Segunda División RFEF Ranking of 13th-place teams

Pos	Team	Pld	W	D	L	GF	GA	GD	Pts	Qualification or relegation
1	Laredo	34	13	6	15	41	36	+5	45
2	Cerdanyola del Vallès (R)	34	11	9	14	45	48	−3	42	Relegation to Tercera División RFEF
3	Gimnástica Segoviana	34	11	9	14	37	42	−5	42	Won the relegation play-offs
4	Don Benito	34	10	11	13	43	42	+1	41
5	Águilas (R)	34	10	11	13	32	36	−4	41	Relegation to Tercera División RFEF

Source:
Rules for classification: 1) points; 2) goal difference; 3) number of goals scored
(R) Relegated