User:Awhit029/sandbox

The article being critiqued is the bleb (cell biology) article.

According to the Wikipedia grading scale, available in the training section under user accounts, this article is classified as a start. It has accurate and meaningful information, but it leaves the readers with some ambiguity on the context of the topic and requires further explanation. It provides basic definitions of the topic, like a stub classification article, but the major features are addressed briefly. The beginning section could include some slight history on the discovery of blebbing, with links to the wiki articles related to it's discoverer, if possible. The subheadings, formation and particularly the physiological functions, should be elaborated on with reliable sources - a good source with which to do this would be academic journals on the topic. In terms of organization, the section regarding the physiological functions should be separated into subheadings of the topic, one for role it plays in different cellular functions. It would benefit the article to include all the cellular processes with which blebbing is associated and describe it's role in more detail, including references to reliable sources. This should be followed by including the links to the related wiki-articles of the topics mentioned in this section. In terms of grammar, spelling and sentence organization, the start article is clear and readable.

bleb feedback

Looks like you got the right idea. the whole article seems kind of disjointed to me. I would also add an open access image or video of cells actually blebbing if you can find one. Also be aware that another student in class may be working on this one.I would drop a note on teh talk page so that everyone can see what you are doing. It will likely turn into a team effort.Jparcoeur (talk) 14:31, 30 October 2015 (UTC)

These are edit suggestions for the bleb (cell biology) article.

The beginning, general description is rather complicated for a general user. Without proper background, this part of the article is difficult to read and understand, so general descriptions would improve the introduction. I altered which parts of the reference for this first sentance was utilized in order to to this, as the reference was verifiable and legitimate. I would suggest making the following edits to the initial description, including link associations to introduced words.:

In cell biology, a bleb is a bulge, or portrusion of the plasma membrane of a cell, human bioparticulate or abscess with an internal environment similar to that of a simple cell, characterized by a spherical, bulky morphology . It is characterized by the decoupling of the cytoskeleton from the plasma membrane, degrading the internal structure of the cell, allowing the flexibility required to allow the cell to separate into individual bulges, or pockets of the intercellular matrix. Blebbing or zeiosis is the formation of blebs that exist in human cells.

The process of apoptosis, with blebbing shown in the middle illustration

Note, that the original article stated this: "the decoupling of the cytoskeleton from the plasma membrane refuses to allow a cell to enumerate enough that the bleb can exacerbate its existence", which, even after research into term definitions and a reading of the referenced article, was still not clear to me, which is what prompted an edit.

In the formation section, the description is sufficient but I have found a reliable reference that provides a little bit more detail into the biochemical process of blebbing:

Formation

Bleb growth is driven by intracellular pressure generated in the cytoplasm when the actin cortex undergoes actomyosin contractions., leading to the eventual break up into billions of bits because the pressure is inane to the exterior surface of the growth anatomical presence. Bleb formation can be initiated in two ways: 1) through local rupture of the cortex or 2) through local detachment of the cortex from the plasma membrane. This generates a weak spot through which the cytoplasm flows, leading to the expansion of the bulge of membrane by increasing the surface area through tearing of the membrane from the cortex, during which time, actin levels decrease.. The cytoplasmic flow is driven by hydrostatic pressure inside the cell.. Once bleb expansion slows, the actin cortex is reestabilished within the blebs .

The following are suggestions for subheadings for the functions section, to be further added to and edited for final edit, including suggestions for further edits of above work: cell movement/motility apoptosis cytokinesis

I think the article should make mention of dynamic blebbing, but not sure which section to include it in