User:DNAenthusiast/sandbox/Claude Gagna
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Claude Gagna.
Claude Gagna, PhD, is an American Professor in the Department of Biological and Chemical Sciences, at the New York Institute of Technology, Old Westbury, NY [1]. He also holds adjunct positions at the Rutgers – New Jersey Medical School [2].
He is a molecular biologist, DNA nanotechnologist and anatomist [1, 2]. Claude Gagna is an active professor in the biological sciences, contributing to both lecture and laboratory learning [3]. He is well known for mentoring high-school, undergraduate, graduate and medical students in research projects leading to peer-reviewed publications with students as co-authors [4, 5]. Along with being a full professor, Claude Gagna focuses much of his time on research involving the structure and function of DNA and RNA, cell death, skin disease and cancer [6, 7, 8, 9]. As an anatomist he publishes clinically-oriented peer-reviewed publications and book chapters on topics such as melanoma, xeroderma pigmentosum and trichothiodystrophy [6, 10, 11, 12]. He and his colleagues recently received an NSF grant for $426, 621.00 in order to purchase a microCT scanner [13] for research, and advancing STEM studies for high school and undergraduates [14, 15].
Claude Gagna has been granted patents for his invention of novel DNA and RNA microarrays in the United States [16, 17, 18] and internationally. These next generation microarrays go beyond conventional gene expression studies and can enhance the "drug discovery" part of drug discovery and development, and DNA structure/function research [19, 20, 21, 22]. His invention allows the immobilization of unaltered, intact, undamaged DNA or RNA onto modified microscope slides used in basic biological research and drug efficacy testing [19, 20, 21, 22, 23, 24, 25]. This achievement resulted in his being awarded the 2006 New Jersey Inventor of the Year [25, 26]. He has also received other awards [4, 25, 27]. He has published numerous peer-reviewed original research-based publications, review articles, book chapters, abstracts, and trade magazines [18, 23, 28, 29, 30, 31, 32]. Additionally, he has published several biology-based undergraduate laboratory manuals via XanEdu Publishers [33, 34]. His research has resulted in citations within Wikipedia pages concerning DNA microarrays and skin pathologies [22, 35]. Claude Gagna has written many editorials and letters to the editors in magazines relating to many different scientific disciplines (36, 37, 38, 39).
Early life and education
Gagna was born in Manhattan and grew up in New York City, Europe and New Jersey. He obtained a Bachelor of Science degree from Saint Peters University in Biology/Natural Sciences, a Master of Science degree in Human Anatomy from Fairleigh Dickinson University – College of Dental Medicine, and a Doctorate degree in Human Anatomy from New York University – Basic Medical Sciences [1, 40]. He completed successful postdoctoral training at the University of Medicine and Dentistry – Medical School in the Departments of Ophthalmology, and Physiology and Pharmacology [1, 7].
Academic career
Gagna advanced in his career by receiving an Adjunct Visiting Research Professorship at Fairleigh Dickinson University, School of Natural Sciences (Biology) in 1998. He then began a tenure-track position in the Department of Life Sciences at New York Institute of Technology in 1999 [1]. He continued his adjunct position at Fairleigh Dickinson University, and then in 1997 received an adjunct position (i.e., Assistant Professor) in the Department of Pathology and Laboratory Medicine at the UMDNJ - Medical School, and in 2009 he was promoted to Associate Professor [30]. Gagna then obtained an adjunct position in the Department of Medicine (i.e., Dermatology) in 2002 [2, 30, 41]. From 2009 to 2013 he was the Administrative Director of the biology teaching labs at NYIT. In 2006 he received tenure and promotion at the New York Institute of Technology (i.e., Associate Professor). In 2020 Gagna was promoted to full professor in the Department of Biological and Chemical Sciences at NYIT. In 2015 he co-founded a chapter of the TriBeta Biology Honor Society at NYIT [42]. He has been an active member in the Symposium on University Research and Creative Expression (SOURCE) since its inception in 2004 [5]. Gagna has also been the advisor to undergraduate students clubs and organizations (i.e., Sponsored Student Organizations), such as the Biomedical Society (2000-2017), Kappa Phi Gamma Society (i.e., Sororities) (2013-2015), American Medical Student Association (2013-present) and Unite For Site (2015-present) [43, 44].
Personal Life
Gagna is married to Judy Gagna, has a daughter, i.e., Olivia Gagna, and lives in Westchester County.
References[edit]
1. NYIT Website: Dr. Gagna, Department of Biological and Chemical Sciences
https://www.nyit.edu/bio/cgagna
2. Rutgers Medical School: Department of Medicine
http://njms.rutgers.edu/departments/medicine/divisions/derm/teaching_staff.cfm
3. Courscle: Undergraduate Courses taught by Claude Gagna
https://www.coursicle.com/nyit/professors/Claude+Gagna/
4. Presidential Engagement Award (2018) - Student Engagement in Research and Scholarship
https://www.nyit.edu/box/Features/presidential_engagement_awards_putting_nyits_best_values_forward
5. SOURCE – 2021 Symposium of University Research and Creative Expression
https://www.nyit.edu/events/source
6. Cutaneous Signs of Disease: Clinics in Dermatology, Volume 29, Issue 5, September
October 2011, Pages 511-522
https://www.sciencedirect.com/science/article/abs/pii/S0738081X11000459
7. Localization of B-DNA and Z-DNA in Terminally Differentiating Fiber Cells in the Adult
Lens - Journal of Histochemistry and Cytochemistry, Vol 45, Issue 11, 1997
https://journals.sagepub.com/doi/full/10.1177/002215549704501108
8. Binding Properties of Bovine Ocular Lens Zeta-Crystallin to Right-Handed B-DNA and
Left-Handed Z-DNA and Single-Stranded DNA. Cell Biology International, Volume 22,
Issue 3, March 1998, Pages 217-225
https://www.sciencedirect.com/science/article/abs/pii/S1065699598902438
9. NYIT Cancer Center – Faculty Researchers (People)
https://comapp.nyit.edu/cancer-research/people
10. Pulse Magazine: The XP Pioneers
Pulse Mag. UMDNJ Winter 2008.pdf
11. Geographic Distribution of Liver and Stomach Cancers in Thailand in Relation to
Estimated Dietary Intake of Nitrate, Nitrite, and Nitrosodimethylamine. Nutrition and
Cancer Volume 60, 2008 - Issue 2.
https://www.tandfonline.com/doi/abs/10.1080/01635580701649636
12. Trichothiodystrophy: Photosensitive, TTD-P, TTD, Tay Syndrome. Diseases of DNA
Repair pp 106-110.
https://link.springer.com/chapter/10.1007/978-1-4419-6448-9_10
13. NSF Grant: MRI: Acquisition of a high-energy micro-computed tomography scanner for
inter- and multi-disciplinary STEM research. Award Abstract # 1828305 (2018)
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828305&HistoricalAwards=false
14. Throwing Light on STEM Innovation – News September 4, 2018
https://www.nyit.edu/box/features/throwing_light_on_stem_innovation
15. NYIT Receives NSF Grant, Aims to Strengthen Regional STEM Innovation.
https://www.nyit.edu/news/news_releases/nyit_receives_nsf_grant_aims_to_strengthen_regional_stem_innovation
16. United States Patent. Patent #: WO2003012124A3, 2002
https://patents.google.com/patent/WO2003012124A3/en
17. Justia Patent: Patents by Inventor Claude Gagna
https://patents.justia.com/inventor/claude-gagna
18. Google Scholar - Peer-Reviewed Publications
https://scholar.google.com/citations?user=QEPHHusAAAAJ&hl=en
19. Using DNA to Revolutionize Drug Discovery.
https://www.nyit.org/box/profiles/faculty_profile_claude_gagna
20. Novel multistranded, alternative, plasmid and helical transitional DNA
and RNA microarrays: implications for therapeutics. Pharmacogenomics. 2009
May;10(5):895-914.
https://pubmed.ncbi.nlm.nih.gov/19450135/
21. Novel drug discovery and molecular biological methods, via DNA,
RNA and protein changes using structure-function transitions: Transitional
structural chemogenomics, transitional structural chemoproteomics and
novel multi-stranded nucleic acid microarray. Med Hypotheses. 2006;67(5):1099-114.
https://pubmed.ncbi.nlm.nih.gov/16828979/
22. DNA Microarray - From Wikipedia, the free encyclopedia.
https://en.wikipedia.org/wiki/DNA_microarray
23. Multistranded, Alternative and Helical Transitional DNA and RNA Microarrays: The
Next Generation.
https://www.americanlaboratory.com/913-Technical-Articles/1226-Multistranded-Alternative-and-Helical-Transitional-DNA-and-RNA-Microarrays-The-Next-Generation/
24. An array of Possibilities – NYIT Magazine, Volume 11, Number 1.
http://www.zhaomiao123.com/files/magazine/NYITMagazine_V11N01_Spring2013.pdf
25. New Jersey’s Inventor Hall of Fame - Inventor of the Year Award, 2006
http://www.njinvent.org/2006-awardees.html
26. New Jersey Inventors Hall of Fame
https://en-academic.com/dic.nsf/enwiki/1822736
27. 2007 Best of Small Tech Awards - 2007 Researcher of the Year runners-up.
https://sst.semiconductor-digest.com/2008/01/2007-best-of-small-tech-awards/
28. Research Gate
https://www.researchgate.net/profile/Claude-Gagna
29. PubMed – National Library of Medicine
https://pubmed.ncbi.nlm.nih.gov/?term=Gagna+CE
30. Novel DNA Staining Method and Processing Technique for the Quantification of
Undamaged Double-stranded DNA in Epidermal Tissue Sections by PicoGreen Probe
Staining and Microspectrophotometry. Journal of Histochemistry & Cytochemistry, Vol
55, Issue 10, 2007.
https://journals.sagepub.com/doi/full/10.1369/jhc.7A7194.2007
31. Use of Anti-Single-Stranded DNA Antibodies to Localize and Quantify Denatured DNA
During Cell Death. Cell Biology International. Volume 24, Issue 9, Pages 657-659
https://onlinelibrary.wiley.com/doi/abs/10.1006/cbir.2000.0574
32. Advanced Techniques for Genomics and Proteomics: Transitional Structural
Chemogenomics, Chemoproteomics, Pharmacogenomics, and Pharmacoproteomics.
American Laboratory, June 5, 2012.
https://www.americanlaboratory.com/913-Technical-Articles/114244-Advanced-Techniques-for-Genomics-and-Proteomics-Transitional-Structural-Chemogenomics-Chemoproteomics-Pharmacogenomics-
and-Pharmacoproteomics/
33. XanEdu Book Publishers.
https://www.xanedu.com/
34. XanEdu Book Publishers.
https://www.researchgate.net/publication/322775754_A_COMPLETE_STUDY_GUIDE_TO_THE_COMPARATIVE_ANATOMY_LABORATORY_TRADITIONAL_INTERDISCIPLINARY_AND_PROBLEM-
BASED_LEARNING_APPROACHES_2017_THIRD_EDITION_ISBN_978-1-50669-839-7_COMPARATIVE_ANATOMY_LABORATOR
35. Braverman's sign – Wikipedia, the free encyclopedia
https://en.wikipedia.org/wiki/Braverman%27s_sign
36. Scientific American - Publish or Perish - Volume 307, Number 4, Page 8.
http://wkbpic.com/wkbx/SA/2012/201210.pdf
37. LetE (Chemical Engineering Progress): The Growth of Biological
Nanotechnology. February 13, 2013
https://www.aiche.org/sites/default/files/cep/20130204.pdf
38. DNA i-motifs – Chemical & Engineering News (Published by the American Chemical
Society). Volume 96, Number 23, Page 3. June 4, 2018.
https://pubs.acs.org/doi/10.1021/cen-ters – AICh09623-reactions
39. Global DNA Banking. New Scientist (Published by Science and
Technology News). Volume 214, Number 2863, Page 28.
https://www.newscientist.com/letter/mg21428630-300-global-banking/
40. Fixation and immunolocalization of left-handed Z-DNA sequences in the calf lens
https://pubmed.ncbi.nlm.nih.gov/1958642/
41. How sildenafil (Viagra ® ) may cause melanoma: a…….
https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.14723
42. TriBeta Biology Honor Society
https://www.nyit.edu/student_resources/beta_beta_beta_national_biological_honor_society
43. American Medical Student Association
https://www.facebook.com/nyitamsa/
44. Unite fir Sight – NYIT Chapter
https://www.facebook.com/NYITUFS
External links[edit]