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user:Lacarubb/RNA binding protein

Wikipedia Project Proposal: RNA-binding proteins

Brianna Lacarubba Eun Young (Anna) Han So hee Kim

Current information on Wikipedia page: Only general definition of RNA-binding protein is present without much detail on its functions, structure and types.

Outline

1) General overview of RNA-binding protein 2) History of RNA-binding protein 3) General structure and an interaction with RNA -Modular design of RNA-binding proteins 4) RNA-binding activity and recognition (specificity) of RNA sequences 5) Diversity of RNA-binding proteins -mRNA binding proteins -snRNA binding proteins -micro-RNA binding proteins

  • Specific examples will be included

6) Post-transcriptional control - Biogenesis - Stability - Function - Transport - Cellular localization

  • Specific examples will be included

7) RNA-binding proteins’ function during germ line and embryonic development 8) Recent findings -Role of RNA-binding protein Sam68 on dendrites -Effects of RNA-binding protein Slr1 on Candida albicans filamentation and virulence -An RNA-binding protein associated with Src in mitosis

Sources for section 4, 7 and 8 (Anna)

http://www.wormbook.org/chapters/www_RNAbindingproteins/RNAbindingproteins.html (RNA-Binding protein in embryonic development)

http://genesdev.cshlp.org/content/3/4/431.full.pdf (RNA-Binding protein and development)

http://www.ncbi.nlm.nih.gov/pubmed/23382180 (current research)

http://www.nature.com/nature/journal/v368/n6474/abs/368867a0.html (current research)

http://www.ncbi.nlm.nih.gov/pubmed/23381995 (current research)

http://www.ncbi.nlm.nih.gov/pubmed/23468662 (current research)

http://www.ncbi.nlm.nih.gov/pubmed/23437386 (current research)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299235/ (RNA binding protein recognition/specificity)

http://rbpdb.ccbr.utoronto.ca/ (RNA-binding protein specificity)

Haned6011 (talk) 17:02, 14 March 2013 (UTC)Haned6011


Bri's review articles:

https://docs.google.com/viewer?a=v&q=cache:gpIFH2udx6EJ:www.oup.com/uk/orc/bin/9780199288373/ch04.pdf+Chapter+04:+The+RNA-binding+proteins+-+Oxford+University+Press&hl=ko&gl=kr&pid=bl&srcid=ADGEESioAC6PHh1UMQJt_dDftmZ3ruodNaxXfQ3Dq7wSCd94ntf9xfFO1sAgwY5EZZQz4VAlnhzW6gVLmSQ_ix6D_fO_1bA1xArSjWlMIaZyXX-o4I0eA7Kz-bzb1EJ6a20HXDNm8BM2&sig=AHIEtbRMHRIzrvkOPm7TPjaG7_2dZ0mnOA

http://www.nature.com/nrm/journal/v3/n3/full/nrm760.html

http://www.nature.com/nrm/journal/v8/n3/full/nrm2124.html#top

http://www.nature.com/nrm/journal/v8/n6/full/nrm2178.html

http://databases.bc.edu:80/V/9Y256VD1B45P99C5GLYU5TAM4B9ANFK875PNH4RLB8K5NX1U5F-04815?func=meta-3&short-format=002&set_number=006524&set_entry=000018&format=999

http://www.wormbook.org/chapters/www_RNAbindingproteins/RNAbindingproteins.html

http://pt7mdv.ceingebi.unam.mx/computo/pdfs/cursosviejos/bcelularII02/bcelular/Dreyfuss.pdf

http://www.ncbi.nlm.nih.gov/books/NBK19709/

http://www.ncbi.nlm.nih.gov/pubmed/18342629

http://europepmc.org/abstract/MED/8036511/reload=0;jsessionid=iUojpYA5fP4WL6wjEb8J.2

http://www.jneurosci.org/content/26/27/7135.full

http://www.nature.com/nrm/journal/v3/n3/full/nrm760.html

http://www.nature.com/nrm/journal/v8/n3/full/nrm2124.html#top

http://www.nature.com/nrm/journal/v8/n6/full/nrm2178.html

Lacarubb (talk) 17:10, 14 March 2013 (UTC)


Work-load distribution:

So hee Kim: Section 1,2,3 Brianna Lacarubba: Section 5,6 Eun Young (Anna) Han: Section 4,7,8


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