User:Mr. Ibrahem/Amfepramone

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Mr. Ibrahem/Amfepramone
Clinical data
Pronunciationdye eth" il proe' pee on
Trade namesTenuate, Tepanil, others
Other namesDiethylpropion, Diethylcathinone
AHFS/Drugs.comMonograph
MedlinePlusa682037
License data
Pregnancy
category
  • AU: B2
Routes of
administration		By mouth
Drug classStimulant[1]
Legal status
Legal status
Pharmacokinetic data
Elimination half-life4-6 hours (metabolites)[4]
ExcretionUrine (>75%)[4]
Identifiers
  • (RS)-2-diethylamino-1-phenylpropan-1-one
Chemical and physical data
FormulaC13H19NO
Molar mass205.301 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • O=C(c1ccccc1)C(N(CC)CC)C
  • InChI=1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3 checkY
  • Key:XXEPPPIWZFICOJ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Amfepramone, also known as diethylpropion, is a medication used in the short-term management of obesity.[5] It is used together with diet and exercise.[5] Use is not recommended beyond a few weeks.[5]

Common side effects include nervousness, trouble sleeping, headache, dry mouth, sweating, nausea, constipation, and thirst.[1] Other side effects may include atrial fibrillation, psychosis, abuse, and pulmonary hypertension.[1] Safety in pregnancy is unclear.[6] It is a stimulant similar to amphetamine.[1]

Amfepramone was approved for medical use in the United States in 1959.[5] It is available as a generic medication.[7] In the United States 30 pills of 75 mg costs about 20 USD.[7] In the United States it is a Schedule IV controlled substance.[1]

References[edit]

  1. ^ a b c d e f "Diethylpropion". LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. 2012. Archived from the original on 6 May 2021. Retrieved 24 December 2021.
  2. ^ "Archive copy" (PDF). Archived (PDF) from the original on 2021-08-27. Retrieved 2021-02-14.{{cite web}}: CS1 maint: archived copy as title (link)
  3. ^ "Amfepramone-containing medicinal products". European Medicines Agency (EMA). 12 February 2021. Archived from the original on 7 March 2021. Retrieved 12 February 2021.
  4. ^ a b "SPC-DOC_PL 16133-0001" (PDF). Medicines Healthcare products Regulatory Agency. Essential Nutrition Ltd. 18 November 2011. Retrieved 18 July 2014.[permanent dead link]
  5. ^ a b c d e "Diethylpropion Monograph for Professionals". Drugs.com. Archived from the original on 21 November 2021. Retrieved 24 December 2021.
  6. ^ "Diethylpropion Use During Pregnancy". Drugs.com. Archived from the original on 20 November 2021. Retrieved 24 December 2021.
  7. ^ a b "Diethylpropion Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 15 November 2016. Retrieved 24 December 2021.
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